This observational study is looking at how the liver's fat (lipid) metabolism changes in people with Alcohol Use Disorder. Researchers will perform a liver biopsy when you first enter a detoxification program and another one about four weeks later, after your liver fat has resolved. They will then compare the genetic activity (transcriptome changes) in your liver between these two time points to understand how alcohol affects liver fat and how it recovers. This study aims to understand the underlying mechanisms of these changes. You may be eligible if you are 18 to 100 years old, enrolled in study 14-AA-0181, seeking inpatient treatment, and have specific liver elasticity measurements (Vibration Controlled Elastography parameters with initial CAP of >295dB/m). The study is currently unclear on its status and plans to enroll 25 participants.

Study design

This is an observational study, not testing a new treatment. It plans to include 25 participants.

What's involved

You would undergo two liver biopsies: one during the first week of admission to a detoxification program and another in the fourth week.

Compensation

Not stated in the trial record.

Follow-up

The primary endpoint is measured between week 1 and week 4 of alcohol cessation, with measurements taken at November 2029.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.