Self-sampling to Optimize Anal Lesion Outcomes

{ "Self-sampling to Optimize Anal Lesion Outcomes Study", "This study is looking for better ways to screen for anal cancer, especially for people at higher risk. Researchers want to see if offering self-sampling (where you collect a sample yourself using a swab) makes it more likely for people to attend their screening appointments, including cytology (a test for abnormal cells) and high-resolution anoscopy (HRA, a closer look at the anal canal). You would be given instructions to collect a sample using a swab, which is then sent to a lab. The study will also compare if choosing between self-sampling or having a healthcare provider collect the sample affects clinic attendance. We are looking for 572 participants, aged 35 or older if HIV-positive, or 45 or older if HIV-negative. The study is currently recruiting.", "design": "This interventional study plans to enroll 572 participants. It will assess how self-sampling affects attendance at cytology and high-resolution anoscopy appointments.", "commitments": "You would receive instructions for self-sampling and collect a sample using a swab. The effect of this intervention will be measured at 1 month for cytology and 2 months for high-resolution anoscopy.", "compensation": "Not stated in the trial record.", "follow_up": "The study will measure the effect of the intervention at 1 month for cytology and 2 months for high-resolution anoscopy.", }

Study design
Not specified.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Not specified.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07192055

Self-sampling to Optimize Anal Lesion Outcomes

Recruiting
NAAges 35+InterventionalPrevention
Medical College of Wisconsin
~572 participants
Updated 2026-05-12 on ClinicalTrials.gov
What's tested:Self-samplingNylon-flocked Swab

At a glance

Recruiting sites
3 of 3 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Effect of the self-sampling intervention at cytology
Measured over 1 month
+1 more outcome measured
Anal Cancer
3 sites across 3 states
Illinois1
Texas1
Wisconsin1
  • Alan Nyitray, PhD · PRINCIPAL_INVESTIGATOR · Medical College of Wisconsin

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  • Effect of the self-sampling intervention at cytology1 month

    Determine the number of individuals who attend the cytology appointment after exposure to the self-sampling intervention.

  • Effect of self-sampling intervention at high-resolution anoscopy2 months

    Determine the number of individuals who attend the high-resolution anoscopy appointment after exposure to the self-sampling intervention.