Study on Harm Reduction for Cigarette Smoking
This study is looking at ways to help people who smoke cigarettes but aren't ready to quit. It compares two approaches: trying harm reduction products (like e-cigarettes or oral nicotine pouches) versus trying medicinal nicotine products (nicotine patches and lozenges). You would be at least 21 years old, smoke at least 5 cigarettes a day, and be able to communicate in English. The main goal is to see if these approaches help people stop smoking after 29 weeks. The study is currently recruiting about 472 participants, but its status is unclear.
- Study design
- This interventional study will randomly assign participants to one of two groups: harm reduction products or medicinal nicotine products. Approximately 472 people are planned to join.
- What's involved
- Participants will try their assigned products for 28 days and complete daily electronic diaries about their smoking and product use.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for 6 months, with smoking abstinence measured at 29 weeks.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Catalyzing Cigarette Smoking Cessation Through Harm Reduction Sampling Among People Unmotivated to Quit
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Janet Audrain-McGovern, Ph.D. · PRINCIPAL_INVESTIGATOR · University of Pennsylvania
Who to contact
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What this trial measures
- Smoking abstinence29 weeks
Seven-day point prevalence smoking abstinence (CO \< 5) will be measured at the 3-month (secondary endpoint) and 6-month follow-up (primary endpoint) via the valid and reliable TLFB procedure and biochemically verified through a CO \< 5 ppm.