Back to search results
NCT07206888

Advanced Ultrasound Signal Processing of Suspicious Breast Images

Enrolling by Invitation
Not specifiedAges 18+Observational
Johns Hopkins University
~252 participants
Updated 2025-10-14 on ClinicalTrials.gov
What's tested:Imaging

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Image quality
Measured over baseline
+5 more outcomes measured

Conditions

Breast Cancer
Breast Cyst
Microcalcification

Explore related trials

Breast CarcinomaBreast CystBreast LumpCalcification of breast

Where it's being run

1 sites across 1 states
Maryland1

Study leadership

  • Muyinatu Bell, PhD · PRINCIPAL_INVESTIGATOR · Johns Hopkins University

Who to contact

This trial hasn't published a contact. View it on ClinicalTrials.gov

Do you actually qualify for this trial?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

Female adults (age \>18 years) with at least one of the following:
Macrocalcification(s) detected in x-ray 2D or 3D mammography images
Macrocalcification(s) located next to cyst (or other identifiable landmark on an ultrasound image)
A cyst, mass, or finding detected in diagnostic/screening ultrasound or mammography

Exclusion

Children (age \< 18 years) are excluded
Children (age \< 18 years) are excluded
Is pregnant
Has open sores including insect bites, rash, poison ivy, and chafing on the skin of the ipsilateral breast
Is experiencing phototoxicity associated with currently taking, or having taken, photosensitizing agents within the previous 72 hours such as sulfonamides, ampicillin, tetracycline
Is currently undergoing phototherapy
Has a history of any photosensitive disease (e.g., porphyria, lupus erythematosus) or is undergoing treatment for a photosensitive disease and is experiencing photosensitivity

What this trial measures

  • Image qualitybaseline

    compare advanced beamforming and benchmark against a conventional beamforming technique by measuring and comparing standard image quality metrics

  • Number of microcalcificationsbaseline
  • Binary visibility of microcalcificationsbaseline

    Clinicians (members of study team) will be shown images and record 'yes' if microcalcifications are present and 'no' if not.

  • Subjective ratingsbaseline

    Clinicians (members of study team) will be shown images and asked to provide subjective ratings of the images

  • Distinction of mass contents: solid vs. fluidbaseline

    After examining the coherence measurements obtained from advanced beamforming techniques, the investigators will determine the ability of this quantitative information to distinguish between solid and fluid-filled masses

  • Distinction of mass contents: benign vs. malignantbaseline

    After examining the coherence measurements obtained from advanced beamforming techniques, the investigators will determine the ability of this quantitative information to distinguish between solid malignant masses vs. solid benign masses