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Acquired Dyslexia Treatment Study

This study is looking at new ways to help people who have developed reading difficulties (acquired dyslexia) after a stroke. Researchers are testing two behavioral therapies: Phono-Motor Therapy (PMT), which focuses on sounds and how they relate to reading, and Semantic Feature Analysis (SFA), which helps you retrieve words by thinking about their meaning. The goal is to see if one treatment works better than the other, based on predictions from a computer model. You might be able to join if you are 18-85 years old, speak English as your first language, had a stroke affecting the left side of your brain, and have reading difficulties. Success will be measured by improvements in reading tests like the Woodcock Reading Mastery Test - III. The study plans to enroll 12 participants, but its current recruitment status is unclear.

Study design
This is a low-risk, early phase 1 study involving 12 participants. All participants will receive two full rounds of treatment.
What's involved
You will receive two rounds of treatment, each lasting 60 hours. This will be spread out over 5 days a week, for 2 hours a day.
Compensation
Not stated in the trial record.
Follow-up
Your reading will be tested at the beginning of the study, after the first 60 hours of therapy, and after the final 60 hours of therapy.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07209488

Acquired Dyslexia Modeling and Treatment

Recruiting
NAAges 18–85InterventionalTreatment
Rutgers, The State University of New Jersey
~12 participants
Updated 2026-05-06 on ClinicalTrials.gov
What's tested:Phono-Motor TherapySemantic Feature Analysis

At a glance

Recruiting sites
3 of 3 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Woodcock Reading Mastery Test - III
Measured over Baseline, following the first 60 hours of therapy, and following the final 60 hours of therapy.
+1 more outcome measured

Conditions

Stroke
Dyslexia, Acquired

Explore related trials

DyslexiaStroke

Where it's being run

3 sites across 3 states
Florida1
Maryland1
New Jersey1

Study leadership

  • William W Graves, PhD · PRINCIPAL_INVESTIGATOR · Rutgers, The State University of New Jersey

Who to contact

William W Graves, PhD
[email protected]
973-353-3947
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Fluent in English as a first language pre-stroke by self report.
Normal or corrected-to-normal vision.
Normal or aided hearing.
Left hemisphere ischemic or hemorrhagic stroke (as verified by a structural brain scan).
Impaired reading as confirmed by significant impairment in the Basic Skills cluster of the Woodcock Reading Mastery Test - III.

Exclusion

Diagnosed pre-stroke neurological disease affecting the brain other than left hemisphere stroke.
Severe apraxia of speech (determined by consensus judgment among speech-language pathologists).
History of learning disabilities such as developmental dyslexia or current self-reported major psychiatric disorders.
Inability to undergo, or provide a copy of, a post-stroke brain imaging scan.

What this trial measures

  • Woodcock Reading Mastery Test - IIIBaseline, following the first 60 hours of therapy, and following the final 60 hours of therapy.

    The WRMT-III is a standardized measure of reading skills.

  • Test words and pseudowordsBaseline, following the first 60 hours of therapy, and following the final 60 hours of therapy.

    Change in accuracy of reading 120 test words and 80 pseudowords