Mild Cognitive Impairment Community Screening and Early Intervention Via Stem Cell Therapy and Wearable Brain Computer Interface Device.
{ "Mild Cognitive Impairment Study: Stem Cell Therapy and Brain-Computer Interface", "This study is looking at new ways to help people with Mild Cognitive Impairment (MCI), which is an early stage of memory or thinking problems. It's testing if early detection in the community, along with treatments like stem cell therapy and a wearable brain-computer interface (BCI) device, can improve cognitive function and slow down the progression to dementia. The study aims to enroll 600 participants aged 55 and older who live in U.S. urban or suburban areas and have suspected or confirmed MCI. You cannot have a formal dementia diagnosis already. Success will be measured by changes in memory and thinking scores (MoCA score) and how many people progress to dementia over time. The current recruitment status is unclear.", "design": "This is a large, randomized, double-blind, placebo-controlled study involving 600 participants. This means participants are randomly assigned to different groups, and neither you nor the study staff will know which treatment you are receiving.", "commitments": "You would participate in structured wellness programs, potentially use a wearable brain-computer interface device, and might receive stem cell therapy or a placebo. You would have cognitive assessments at baseline, 6 months, 1 year, and annually for up to 5 years.", "compensation": "Not stated in the trial record.", "follow_up": "Participants will be followed for up to 5 years, with annual assessments to track cognitive function and progression to dementia.", }
- Study design
- Not specified.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- Not specified.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Mild Cognitive Impairment Community Screening and Early Intervention Via Stem Cell Therapy and Wearable Brain Computer Interface Device.
At a glance
Conditions
Where it's being run
1 sites across 1 statesWho to contact
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What this trial measures
- Change in Cognitive Function as Measured by MoCA ScoreBaseline, 6 months, 1 year, and annually up to 5 years.
The primary endpoint is the mean change from baseline in Montreal Cognitive Assessment (MoCA) total score, assessing domains such as memory, attention, language, and executive function. A clinically meaningful improvement is defined as an increase of ≥3 points, while decline indicates progression. This measure evaluates the efficacy of interventions in stabilizing or enhancing cognitive performance.
- Rate of Progression to DementiaAssessed annually over 5 years.
Proportion of participants progressing from MCI to dementia (e.g., Alzheimer's disease or other forms), diagnosed via DSM-5 criteria and confirmed by neuropsychological evaluation. This assesses intervention effectiveness in delaying or preventing cognitive decline.