Exercise and the Tumor Microenvironment in Lung Cancer
This study is investigating how exercise might affect the tumor microenvironment (TME) in patients with non-small cell lung cancer. The TME is the complex environment around a tumor, including cells and other factors that can influence how a tumor grows and responds to treatment. Researchers believe that strenuous exercise could change the TME and the genetic makeup of the tumor, potentially improving the body's immune response against the cancer. They will measure the TME at different times, including before surgery and up to 24 months afterward, to see if exercise makes a difference. You may be able to join if you have lung cancer and are at low risk for exercise testing. The study plans to enroll 48 participants, but its current recruitment status is unclear.
- Study design
- This is an interventional study, meaning participants will receive a specific intervention. It aims to enroll 48 participants.
- What's involved
- You will be offered a lab exercise regimen. For a specific part of the study, only three or four visits are needed, totaling about 4 hours of your time. The first visit is for pre-exercise screening.
- Compensation
- Not stated in the trial record.
- Follow-up
- The tumor microenvironment will be measured at baseline, around the time of surgery, and for up to 24 months afterward.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
The Impact of Exercise on the Tumor Microenvironment in Patients With Lung Cancer
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Stephanie Worrell, MD · PRINCIPAL_INVESTIGATOR · University of Arizona
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Tumor MicroenvironmentBaseline, Perioperative, up to 24 months
Lung cancer specimens will be collected from all patients at the time of surgery. Investigators will perform real-time PCR to identify levels of PDL-1