Understanding Myocardial Stiffness in Amyloidosis
This study is looking at a new way to measure heart stiffness in people with amyloidosis (a condition where abnormal proteins build up in organs). It uses a special type of MRI called Magnetic Resonance Elastography (MRE) to see if this method is useful. We want to see how many people can successfully complete the MRE exam and measure the average heart stiffness. You might be able to join if you are an adult (20 years or older), are medically stable, and can give your consent. The study is currently unclear on its recruitment status and plans to enroll 20 participants.
- Study design
- This is an observational study, meaning participants will be observed without receiving a new treatment. It aims to enroll 20 participants.
- What's involved
- You will undergo a cardiac MRI, which includes special MRE sequences. This involves continuous free-breathing and breath-held MRE sequences.
- Compensation
- Not stated in the trial record.
- Follow-up
- Measurements for the study's main goals, like completing the MRE exam and measuring heart stiffness, are taken at Baseline (the start of the study).
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
A Study Of Myocardial Stiffness In Amyloidosis With Magnetic Resonance Elastography
At a glance
Conditions
NCT07216469
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
Mayo Clinic
Rochester, Minnesotastudy coordinator listed
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- Ian Chang, M.D. · PRINCIPAL_INVESTIGATOR · Mayo Clinic
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- Percentage of subjects able to complete a Magnetic Resonance Elastography examBaseline
Magnetic Resonance Elastography exam completion will be determined by signal to noise (SNR) ratio
- Mean Myocardial StiffnessBaseline
Mean Myocardial stiffness will be measured by magnetic resonance elastography during early systole, end systole, early diastole and end diastole (kPa).