Remapping Text to Aid Reading with Central Vision Loss

This study is testing new ways to help people with central vision loss, like from macular degeneration, read more easily. It's looking at different behavioral training methods called "Personalised Remapping Training," "RSVP personalized remapping," and "Reading text in the wild with remapping." These methods shift text away from blurry areas in your vision to clearer spots. The study aims to see if these trainings can improve how fast and accurately you can read sentences and words. To join, you need to be at least 16 years old and have dense central blind spots (scotomas) in both eyes that are at least 2 degrees wide. The study plans to enroll 100 participants, but its current status is unclear.

Study design
This interventional study plans to enroll 100 participants. It will test different remapping strategies for reading.
What's involved
You will have an initial visit for consent and an eye exam, followed by mapping your scotomas. You will then participate in various reading tasks with and without remapping, including different training sessions over multiple days.
Compensation
Not stated in the trial record.
Follow-up
Sentence reading speed and accuracy will be measured at day 35, and word reading speed at day 21, marking the end of specific intervention periods.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07216924

Remapping Text in Sentence and Word Tasks to Aid Reading With Central Vision Loss

Not Yet Recruiting
NAAges 16+InterventionalBasic science
University of Minnesota
~100 participants
Updated 2026-07-07 on ClinicalTrials.gov
What's tested:Personalised Remapping TrainingRSVP personalized remappiReading text in the wild with remapping

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Sentence reading speed
Measured over Measured on day 35, end of the Personalised Remapping Training in the 33 participants in the Perceptual Learning arm.
+5 more outcomes measured
Macular Degeneration
Central Visual Impairment

NCT07216924

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • University of Minnesota

    Edina, Minnesotastudy coordinator listed

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

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Eligibility criteria

Inclusion

Dense bilateral scotomas of at least 2 deg diameter in each eye covering the fovea
Bivariate contour ellipse area (BCEA) of less than 10\^2 is obtained in a simple fixation task

Exclusion

Neovascular AMD
Any history of visual disorders other than that causing the central vision loss.
  • Sentence reading speedMeasured on day 35, end of the Personalised Remapping Training in the 33 participants in the Perceptual Learning arm.

    Time it took to read sentence in words per minute

  • Sentence reading accuracyMeasured on day 35, end of the Personalised Remapping Training in the 33 participants in the Perceptual Learning arm.

    Percentage of correctly read words in sentence

  • Word reading speed: RSVPMeasured on day 21, end of the RSVP Remapping intervention in the 33 participants in the Rapid Serial Visual Presentation arm.

    Time taken to read each word

  • Word recognition accuracy: RSVPMeasured on day 21, end of the RSVP Remapping intervention in the 33 participants in the Rapid Serial Visual Presentation arm.

    Percentage of words correctly read

  • Word reading speed: Reading in The WildMeasured on day 21, end of the Reading Text in The Wild with Remapping intervention in the 33 participants in the Reading in The Wild arm.

    Time taken to read each word

  • Word recognition accuracy: Reading in the wildMeasured on day 21, end of the Reading Text in The Wild with Remapping intervention in the 33 participants in the Reading in The Wild arm.

    Percentage of words correctly read