NCT07217080
The Effect of Thalamic Stimulation on Sleep Oscillations
Enrolling by Invitation
NAAges 5–85InterventionalBasic scienceMassachusetts General HospitalInvestigator-initiated
~50 participants
Updated 2025-10-15 on ClinicalTrials.gov
What's tested:Effect of Electrical Stimulation on Sleep
At a glance
Recruiting sites
0 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change from pre-stimulation baseline of sleep spindle rate
Measured over 10 to 3000 milliseconds following stimulation
Conditions
Where it's being run
2 sites across 1 statesMassachusetts2
Study leadership
- Rina Zelmann, Ph.D. · PRINCIPAL_INVESTIGATOR · Massachusetts General Hospital
Who to contact
This trial hasn't published a contact. View it on ClinicalTrials.gov
Do you actually qualify for this trial?
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Eligibility criteria
Inclusion
Patients getting intracranial recordings for clinical purposes who, as part of that plan, will receive thalamic electrodes.
Exclusion
previous extensive resection or large atrophy
What this trial measures
- Change from pre-stimulation baseline of sleep spindle rate10 to 3000 milliseconds following stimulation
An increase in spindle rate is achieved if at least 50% of trials evoke a spindle as measured on intracranial EEG following stimulation. A spindle is evoked when the power in the 10-16Hz band is larger than pre-stimulation baseline power by at least 2 standard deviations.