Rutgers University Study of the Genetics of Pulmonary Hypertension

This observational study from Rutgers University aims to understand how your genes might affect your risk of developing pulmonary hypertension (PH), a condition where blood pressure in the arteries leading to your lungs is too high. You can join if you are 18 or older, live in the US, and have internet access. You don't need to have PH to participate. The study involves providing a saliva sample for DNA analysis and completing health surveys online. The main goal is to identify genetic differences linked to PH over two years. The study is currently recruiting 10,000 participants, but its exact status is unclear.

Study design
This is an observational study aiming to enroll 10,000 participants to learn about genetic risk factors for pulmonary hypertension.
What's involved
You will complete online health surveys and provide a saliva sample using a kit mailed to your home. This takes about 20 minutes.
Compensation
You may opt to receive information about your genetic ancestry at no cost.
Follow-up
Genetic risk variants associated with pulmonary hypertension will be measured at 2 years.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07217522

Rutgers University Study of the Genetics of Pulmonary Hypertension

Recruiting
Not specifiedAges 18+Observational
Rutgers, The State University of New Jersey
~10,000 participants
Updated 2025-11-03 on ClinicalTrials.gov
What's tested:Saliva sampleHealth surveys

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Genetic risk variants associated with pulmonary hypertension
Measured over 2 years
Pulmonary Hypertension
Pulmonary Arterial Hypertension
Pulmonary Arterial Hypertension (PAH) (WHO Group 1 PH)
Pulmonary Arterial Hypertension Associated With Connective Tissue Disease
Pulmonary Arterial Hypertension Associated With Connective Tissue Disease (Disorder)
Pulmonary Arterial Hypertension Associated With Schistosomiasis (Disorder)
Pulmonary Arterial Hypertension of Congenital Heart Disease
Pulmonary Arterial and Chronic Thromboembolic Pulmonary Hypertension
1 sites across 1 states
New Jersey1
  • Tara Matise, Ph.D. · PRINCIPAL_INVESTIGATOR · Rutgers, The State University of New Jersey

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

age 18 years or older
currently living in the United States
able to understand and follow written instructions in English
have access to the internet and a computer, laptop, tablet or smart phone
willing to provide written informed consent for participation
willing to provide DNA via a saliva sample using a collection kit mailed to the study participant's home
willing to complete a survey with questions about health related to the study of pulmonary hypertension.

Exclusion

Age 17 or below
Not currently living in the United States
Not able to participate in an online research study in English
  • Genetic risk variants associated with pulmonary hypertension2 years

    Genetic factors will be measured through whole exome sequencing along with genotyping of common variants, and then correlated with pulmonary hypertension and pulmonary hypertension subtype.