Back to search results
NCT07218094

Neuromechanical Mechanisms of Exosuit-assisted Gait Rehabilitation After Stroke

Enrolling by Invitation
NAAges 18+Interventional
Boston University Charles River Campus
~22 participants
Updated 2026-08-11 on ClinicalTrials.gov
What's tested:Walking with robotic ankle assistance

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Dynamic Motor Control Index (DMCI)
Measured over Baseline, Assisted (on average 1-2 hours)
+4 more outcomes measured

Conditions

Stroke

Explore related trials

Gait Disorders, NeurologicStroke

NCT07218094

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Boston University Neuromotor Recovery Laboratory

    Boston, Massachusettsno site contact published

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Study leadership

  • Louis N Awad, PT, DPT, PhD · PRINCIPAL_INVESTIGATOR · Boston University Charles River Campus

Who to contact

This trial hasn't published a contact. View it on ClinicalTrials.gov

Want this trial checked against your situation?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

At least 18 years old
\>6 months post-stroke
Observable gait deficits
Able to walk overground and on a treadmill without body-weight support
Able to communicate clearly with investigators and follow instructions
Able to fit the exosuit components, including height between 4'8" and 6'7", weight \< 264lbs, neutral ankle dorsiflexion during standing.

Exclusion

Comorbidities besides stroke that impair walking (musculoskeletal, cardiovascular, pulmonary, or neurological)
Severe pain, neglect, hemianopia, or aphasia limiting comprehension
Unexplained dizziness or more than 2 falls in the previous month
Inability to communicate (as assessed by a licensed physical therapist)
Inability to wear the exosuit due to conditions that require medical management, such as open wounds or broken skin, or as assessed by a licensed physical therapist.

What this trial measures

  • Dynamic Motor Control Index (DMCI)Baseline, Assisted (on average 1-2 hours)

    Difference in neuromuscular control quality compared to normative data with and without exosuit

  • Correlation Between Propulsion and Weight-Acceptance Motor Modules (Temporal)Baseline, Assisted (on average 1-2 hours)

    Difference in the merging of motor module structures quantified by correlation coefficient between the propulsion temporal module and weight-acceptance temporal module, computed from EMG data by non-negative matrix factorization, with and without exosuit

  • Correlation Between Weight-Acceptance and Swing-Limb Deceleration Motor Modules (Temporal)Baseline, Assisted (on average 1-2 hours)

    Difference in the merging of motor module structures quantified by correlation coefficient between the weight-acceptance temporal module and swing-limb deceleration temporal module, computed from EMG data by non-negative matrix factorization, with and without exosuit

  • Variance Accounted For (VAF) by Four Muscle SynergiesBaseline, Assisted (on average 1-2 hours)

    Difference in the variance in muscle activation accounted for by the 4-synergy model, measuring the quantitative shift in muscle coordination complexity with and without exosuit (%)

  • Paretic PropulsionBaseline, Assisted (on average 1-2 hours)

    Difference in anterior-posterior ground reaction force with and without exosuit (N)