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Pistachio Consumption and Sleep Quality Study

This study is looking at whether eating pistachios can improve sleep quality. Researchers are comparing people who eat pistachios daily to those who eat control foods (muffins and cookies without nuts) for four weeks. They want to see if pistachios affect how well people sleep, both by what they report and by objective measures, and if it impacts melatonin production (a hormone that helps with sleep). You might be able to join if you are between 45 and 64 years old, have poor sleep quality (a score over 5 on the Pittsburgh Sleep Quality Index), and have a BMI between 20 and 29.9. The study is looking for 28 participants, but its current recruitment status is unclear.

Study design
This is an interventional study, meaning participants will receive a specific intervention. It plans to enroll 28 participants to compare pistachio consumption against a control food.
What's involved
Participants will eat study foods (pistachios or control foods) daily for 4 weeks. They will also need to stop taking vitamin and mineral supplements.
Compensation
Not stated in the trial record.
Follow-up
Sleep quality and melatonin production will be measured at 4 weeks, which is the end of the intervention period.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07218822

Impact of Pistachio Consumption on Sleep

Recruiting
NAAges 45–64InterventionalTreatment
Columbia University
~28 participants
Updated 2026-02-13 on ClinicalTrials.gov
What's tested:PistachioControl food

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Self-reported sleep quality
Measured over 4 weeks
+2 more outcomes measured

Conditions

Poor Quality Sleep

Explore related trials

Quality of sleep

NCT07218822

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Columbia University Irving Medical Center

    New York, New Yorkstudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Study leadership

  • Marie-Pierre St-Onge · PRINCIPAL_INVESTIGATOR · Columbia University

Who to contact

Diane Hawkins
[email protected]
347-963-8845
Email the study team

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Eligibility criteria

Inclusion

Poor sleep quality, Pittsburgh Sleep Quality Index score \>5
BMI 20 - 29.9 kg/m\^2
Ability to abstain from travel across time zones
Willingness to eat study foods
Willingness/ability to discontinue use of vitamin and mineral supplements

Exclusion

Premenopausal women
Medical or living conditions that could affect sleep:
Smoking
Excessive caffeine intake (\>300 mg/day)
Non-day shift work
Chronic pain
Diagnosis of a chronic disease (e.g., uncontrolled hypertension, pre-diabetes, type 2 diabetes, chronic kidney disease, chronic obstructive pulmonary disease)
Autoimmune diseases, cardiovascular event or cancer in the past 24 months
Psychiatric/neurologic disease or disorder, or sleep disorder (diagnosed or high risk for sleep apnea, chronic insomnia, restless leg syndrome, narcolepsy)
Allergy or intolerance to nuts or study foods
Use of medications that influence CYP1A2 and selective serotonin reuptake inhibitors

What this trial measures

  • Self-reported sleep quality4 weeks

    Self-reported sleep quality will be reported by the score on the Pittsburgh Sleep Quality Index. The full score range is 0 to 21, where a higher score indicates worse sleep quality.

  • Objective sleep quality4 weeks

    Sleep fragmentation index assessed by wrist actigraphy. This is a measure of how frequently sleep is interrupted, calculated as the sum of the percentage of all scored epochs with one or more activity counts during time in bed and percentage of one-minute periods of sleep vs all periods of sleep during the sleep period.

  • Overnight melatonin production4 weeks

    Amount of 6-sulfatoxymelatonin present in urine collected overnight, reported as ng/mg creatinine (corrected for creatinine content).