Boosting Exercise Adherence in Knee Osteoarthritis (BOOST-OA)

This study is for Veterans with knee osteoarthritis (OA), a condition causing knee pain and stiffness. It's testing an intervention called BOOST-OA to help people stick with their home exercise programs while receiving physical therapy (PT). The study aims to see if BOOST-OA can improve your physical function, like walking and climbing stairs. You might be eligible if you have a diagnosis of knee OA, knee pain for at least three months, and some difficulty with walking or stairs. The main way success will be measured is by looking at changes in your physical function over 12 months using a survey called the Western Ontario and McMaster Universities Arthritis Index (WOMAC) Physical Function Subscale. The current recruitment status is unclear, but the study plans to enroll 360 participants.

Study design
This study is an interventional trial that plans to enroll 360 participants. It compares BOOST-OA with usual physical therapy care.
What's involved
You would receive at least four physical therapy visits. The BOOST-OA intervention includes components during and after your physical therapy visits, lasting for 12 months.
Compensation
Not stated in the trial record.
Follow-up
Your physical function will be measured at baseline, 3 months, and 12 months after starting the study.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07219732

Boosting Exercise Adherence in Knee Osteoarthritis

Not Yet Recruiting
NAAges 18+InterventionalTreatment
VA Office of Research and Development
~360 participants
Updated 2026-07-23 on ClinicalTrials.gov
What's tested:Usual PT Care (UC)BOOST-OA

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Western Ontario and McMaster Universities Arthritis Index (WOMAC) Physical Function Subscale
Measured over Baseline
+4 more outcomes measured
Osteoarthritis, Knee
1 sites across 1 states
North Carolina1
  • Kelli Dominick Allen, PhD · PRINCIPAL_INVESTIGATOR · Durham VA Medical Center, Durham, NC

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  • Western Ontario and McMaster Universities Arthritis Index (WOMAC) Physical Function SubscaleBaseline

    The investigators selected physical function as the primary outcome because of its high importance to individuals with knee OA and its relevance for PT and exercise-based interventions. The WOMAC has been used widely in the context of clinical trials for knee OA and has well established psychometric properties including reliability, construct validity, internal consistency, and sensitivity to change in the context of behavioral interventions for knee OA. The WOMAC function subscale consists of 17 items rated on a Likert scale of 0 (no difficulty) to 4 (extreme difficulty).

  • Western Ontario and McMaster Universities Arthritis Index (WOMAC) Physical Function SubscaleChange from baseline to 3-months

    The investigators selected physical function as the primary outcome because of its high importance to individuals with knee OA and its relevance for PT and exercise-based interventions. The WOMAC has been used widely in the context of clinical trials for knee OA and has well established psychometric properties including reliability, construct validity, internal consistency, and sensitivity to change in the context of behavioral interventions for knee OA. The WOMAC function subscale consists of 17 items rated on a Likert scale of 0 (no difficulty) to 4 (extreme difficulty).

  • Western Ontario and McMaster Universities Arthritis Index (WOMAC) Physical Function SubscaleChange from baseline to 12-months (primary outcome time point)

    The investigators selected physical function as the primary outcome because of its high importance to individuals with knee OA and its relevance for PT and exercise-based interventions. The WOMAC has been used widely in the context of clinical trials for knee OA and has well established psychometric properties including reliability, construct validity, internal consistency, and sensitivity to change in the context of behavioral interventions for knee OA. The WOMAC function subscale consists of 17 items rated on a Likert scale of 0 (no difficulty) to 4 (extreme difficulty).

  • Western Ontario and McMaster Universities Arthritis Index (WOMAC) Physical Function SubscaleChange from baseline to 18-months

    The investigators selected physical function as the primary outcome because of its high importance to individuals with knee OA and its relevance for PT and exercise-based interventions. The WOMAC has been used widely in the context of clinical trials for knee OA and has well established psychometric properties including reliability, construct validity, internal consistency, and sensitivity to change in the context of behavioral interventions for knee OA. The WOMAC function subscale consists of 17 items rated on a Likert scale of 0 (no difficulty) to 4 (extreme difficulty).

  • Western Ontario and McMaster Universities Arthritis Index (WOMAC) Physical Function SubscaleChange from baseline to 24-months

    The investigators selected physical function as the primary outcome because of its high importance to individuals with knee OA and its relevance for PT and exercise-based interventions. The WOMAC has been used widely in the context of clinical trials for knee OA and has well established psychometric properties including reliability, construct validity, internal consistency, and sensitivity to change in the context of behavioral interventions for knee OA. The WOMAC function subscale consists of 17 items rated on a Likert scale of 0 (no difficulty) to 4 (extreme difficulty).