Accelerated iTBS Targeting of Working Memory Versus Inhibitory Control in Adolescent ADHD
{ "iTBS for Adolescent ADHD", "This study is testing a treatment called intermittent theta burst stimulation (iTBS), a type of repetitive transcranial magnetic stimulation, for adolescents with ADHD. Researchers want to see if targeting different brain areas (left DLPFC versus right PreSMA) can better help with working memory or inhibitory control problems. Fifty adolescents, aged 12-18, with an ADHD diagnosis and reported difficulties with working memory and inhibitory control, can join. You would receive iTBS three times a day for ten days. Success will be measured by changes in brain activity (EEG and fMRI) and how well participants perform on tasks that test working memory and inhibitory control after the treatment.", "design": "This is an interventional study planning to enroll 50 participants. Participants will be randomly assigned to receive iTBS targeting either the left DLPFC or right PreSMA.", "commitments": "You would receive iTBS treatments three times a day for a total of ten days (30 sessions). You will also have brain scans (EEG and fMRI) and complete tasks to measure working memory and inhibitory control around 1-2 days after your last iTBS session.", "compensation": "Not stated in the trial record.", "follow_up": "Measurements of brain activity and task performance will be taken approximately 1-2 days after the iTBS treatment.", }
- Study design
- Not specified.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- Not specified.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Accelerated iTBS Targeting of Working Memory Versus Inhibitory Control in Adolescent ADHD
At a glance
Conditions
Where it's being run
1 sites across 1 statesWho to contact
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What this trial measures
- EEG, source-localized oscillatory beta band bursting during SST/SWMTVisit 13, approximately 1-2 days after iTBS
PreSMA-targeted iTBS will lead to greater relative activation of the IC network versus the WM network (and the opposite pattern for DLPFC-targeted iTBS).
- fMRI-measured blood oxygenation level-dependent (BOLD) activity during SST/NBTVisit 13, approximately 1-2 days after iTBS
PreSMA-targeted iTBS will lead to greater relative activation of the IC network versus the WM network (and the opposite pattern for DLPFC-targeted iTBS).
- Task-based WM/IC performance on SWMT/N-Back/SSTVisit 13, approximately 1-2 days after iTBS
PreSMA-targeted iTBS will lead to greater relative improvement of IC versus WM (and the opposite pattern for DLPFC-targeted iTBS)
- Rater-Based WM/IC symptoms (BRIEF-2)Visit 13, approximately 1-2 days after iTBS
PreSMA-targeted iTBS will lead to greater relative improvement of IC versus WM (and the opposite pattern for DLPFC-targeted iTBS)