NCT07219888
Comparison of Suzetrigine and Oxycodone for Postoperative Pain After Primary Total Knee Arthroplasty
Enrolling by Invitation
PHASE4Ages 21–89InterventionalBasic scienceUniversity of LouisvilleInvestigator-initiated
~140 participants
Updated 2026-05-04 on ClinicalTrials.gov
What's tested:oral suzetrigineoral Oxycodone
At a glance
Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Daily Opioid Use POD 1-14
Measured over 2 weeks
+4 more outcomes measured
Conditions
Where it's being run
1 sites across 1 statesKentucky1
Study leadership
- Rodolfo Zamora, MD · STUDY_CHAIR · University of Louisville
Who to contact
This trial hasn't published a contact. View it on ClinicalTrials.gov
What this trial measures
- Daily Opioid Use POD 1-142 weeks
Daily opioid use as measured in MME recorded daily for the first two weeks following TKA
- total opioid usage over two weeks2 weeks
total daily opioid usage (as measured in MME) for the first 14 days following TKA
- Use of supplemental opioid POD 1-142 weeks
Average time from initial preop pain control dose to first postop supplemental opioid dose (for participants randomized to Group A, if applicable)
- VAS pain score over two weeks2 weeks
VAS (Visual Analogue Scale) pain score measuring highest level of knee pain experienced each day for the first 14 days following TKA. Scale 0-10
- Opioid Usage at 6 weeks postop6 weeks
Usage of opioids at 6 weeks postoperatively (Y/N) and if yes, what is daily usage