Gut Mini-Pill Study for Diet and Microbiota
This study is testing a new way to understand how your diet affects your gut bacteria (microbiota). Researchers are using a small, swallowable device called a "mini-pill" to collect samples from different parts of your digestive system. You would eat either plant-based meat alternative entrees or meat-based entrees. The main goal is to see if these mini-pills can successfully show changes in your gut bacteria after eating these different diets over 8 weeks. To join, you should be between 50 and 75 years old, a man or postmenopausal woman, and have normal digestive, kidney, and liver function. You also need to be willing to swallow the mini-pills and collect stool samples. The study's status is currently unclear.
- Study design
- This is a randomized-controlled double-blind crossover trial with a planned enrollment of 30 participants. It involves two phases where participants will switch between diets.
- What's involved
- You would consume provided meals (either meat or plant-based meat alternatives) for up to 3 weeks in each phase. After 2 weeks on each diet, you would swallow 6 mini-pills and collect stool samples until all mini-pills are recovered, which can take 2 to 6 days.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary goal is measured at 8 weeks, indicating follow-up for at least that duration.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Gut Mini-Pill Study
At a glance
Conditions
NCT07220369
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
Jean Mayer Human Nutrition Research Center on Aging
Boston, Massachusettsstudy coordinator listed
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- Alice H Lichtenstein, D.Sc. · PRINCIPAL_INVESTIGATOR · Tufts University
Who to contact
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Inclusion
Exclusion
What this trial measures
- Test feasibility of the mini-pill to characterize differential changes inducted by a meat-rich and plant-based meat alternative-rich diet on the gut microbial profile8 weeks
Using luminal content collected by the gut mini-pill to compare the microbiome and metabolome after subjects consumed a meat-rich and plant-based meat alternative-rich diet