Online Intervention for Misophonia

This study is testing an online program called Acceptance and Commitment Therapy (ACT) for adults with misophonia (strong negative reactions to certain sounds). The main goal is to see if this online program works better than a waiting list and if people find it easy to use. You might be able to join if you are at least 18 years old, live in the United States, speak fluent English, and have misophonia that affects your daily life. You cannot join if you are currently getting other therapy for misophonia or have recently changed psychiatric medications. Success will be measured by how your misophonia symptoms change after 16 weeks, using a tool called the Selective Sound Sensitivity Syndrome Scale (S-Five). The current recruitment status is unclear, but 100 people are planned to enroll.

Study design
This is an interventional study where 100 participants will be randomly assigned to either receive the online intervention or be on a waiting list.
What's involved
If you are in the intervention group, you will complete an 8-module online program and 5 surveys over 4 months. If you are in the waitlist group, you will complete 5 surveys over 4 months and then get access to the program.
Compensation
Not stated in the trial record.
Follow-up
Your misophonia symptoms will be measured at 16 weeks, and other outcomes will be assessed at baseline, mid-intervention, post-intervention, and one- and two-month follow-up.

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NCT07220941

Digital Intervention for Adults With Misophonia: A Randomized Controlled Trial

Recruiting
NAAges 18+InterventionalTreatment
Utah State University
~100 participants
Updated 2025-10-24 on ClinicalTrials.gov
What's tested:Acceptance and commitment therapy

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Selective Sound Sensitivity Syndrome Scale (S-Five; Vitoratou et al., 2021)
Measured over 16 weeks
Misophonia
1 sites across 1 states
Utah1
  • Emily M Bowers, M.S. · PRINCIPAL_INVESTIGATOR · Utah State University

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Eligibility criteria

Inclusion

Currently meet clinical impairment for misophonia.
At least 18 years old.
Fluent English speakers.
Currently live or reside in the United States

Exclusion

Currently receiving alternative psychotherapy for misophonia.
Currently modifying or starting psychotropic medication (within 30 days of starting the study).
Any psychological and/or neurological impairments that would preclude someone from participating in the study (e.g.,active self-harm or psychosis)
  • Selective Sound Sensitivity Syndrome Scale (S-Five; Vitoratou et al., 2021)16 weeks

    The S-Five is a 25-item self-report measure of misophonia severity. Items (e.g., "I feel trapped if I cannot get away from certain noises") are rated on a 0 (not at all true) to 10 (completely true) ordinal scale with total scores ranging from 0 to 250. The S-Five consists of five latent factors: (1) externalizing appraisals (e.g., blaming others for making sounds), (2) internalizing appraisals (e.g., negative self-judgments triggered by misophonia), (3) impact on functioning (e.g., social and occupational impact), (4) outburst (e.g., experiences of aggression or fear of losing control), and (5) threat (e.g., feeling trapped or helpless). The S-Five demonstrates good internal consistency and convergent validity with other misophonia measures (Vitoratou et al., 2023).