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Dietary Education for Vascular Health: Sodium vs. Potassium

This study is looking at whether increasing potassium in your diet is a better way to improve your heart and blood vessel health compared to reducing sodium (salt) in your diet. Researchers want to see if it's easier for healthy young adults, who typically eat a lot of salt, to increase their potassium intake rather than cut down on sodium. You could join if you are between 18 and 45 years old, eat more than the recommended amount of sodium, and less than the recommended amount of potassium. The study will compare two types of education: one focused on increasing potassium and the other on decreasing sodium. Success will be measured by changes in how much sodium and potassium you eat, and how much sodium is in your urine.

Study design
This is an interventional study with 32 participants. You would be randomly assigned to receive education on either increasing potassium or decreasing sodium.
What's involved
You would receive four weekly individualized education sessions. Follow-up visits will occur every two months for six months after the education period.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for six months after the education period to measure dietary changes and cardiovascular health.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07221448

Sodium vs Potassium Education to Improve Vascular Health

Recruiting
NAAges 18–45InterventionalPrevention
Florida State University
~32 participants
Updated 2026-04-23 on ClinicalTrials.gov
What's tested:High potassium dietary education/counselingLow sodium dietary education/counseling

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in dietary sodium intake
Measured over Baseline; 2 month, 4month, 6month
+5 more outcomes measured

Conditions

Healthy

Explore related trials

Healthy

Where it's being run

1 sites across 1 states
Florida1

Study leadership

  • Andrea Lobene, PhD, RD, LD · PRINCIPAL_INVESTIGATOR · Florida State University

Who to contact

Andrea Lobene, PhD, RD, LD
[email protected]
850-644-1829
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Willing and able to attend in-person laboratory visits
Usual sodium intake ≥3,000 mg/d for females and ≥4,000 mg/d for males
Usual potassium intake ≤2,500 mg/d in females and ≤3,000 mg/d in males

Exclusion

BMI ≥35 kg/m2
Seated blood pressure ≥130/80 mmHg
Current diagnosis or history of diabetes, renal disease, cancer, cardiovascular disease, or major cardiovascular event (e.g. heart attack or stroke)
Current or recent use of a diuretic (within the past 6 months)
Elevated blood lipids (LDL cholesterol ≥190 mg/dL)
Elevated serum potassium level (\>5.1 mmol/L)
Elevated BUN (\>22 mg/dL)
Elevated creatinine (\>1.2 mg/dL)
Low eGFR (\<90 mL/min/1.73 m²)
Current or recent use of tobacco, nicotine, or illicit drugs
Radical hysterectomy or oophorectomy (females)\*
Pregnant or lactating
Following a weight-loss diet, or intending to gain or lose weight during the study period

What this trial measures

  • Change in dietary sodium intakeBaseline; 2 month, 4month, 6month

    Dietary sodium intake will be assessed via participant self-reported 3 day diet record

  • Change in dietary potassium intakeBaseline, 2month, 4month, 6month

    Dietary potassium intake will be assessed via participant self-reported 3-day diet record

  • Change in 24-hour urinary sodium excretionBaseline, 2month, 4month, 6month

    Urinary sodium excretion obtained from 24-hour urine sample

  • Change in 24-hour urinary potassium excretionBaseline, 2month, 4month, 6month

    Urinary potassium excretion measured from 24-hour urine sample

  • Change in Blood pressureBaseline; 2 month, 4month, 6month

    Seated, automated blood pressure mmHg

  • Change in Endothelial functionBaseline; 2 month, 4month, 6month

    brachial artery flow-mediated dilation as measured in % dilation