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Songwriting for Anxiety in Adolescents with Sickle Cell Disease

This study is looking at whether a songwriting intervention (active music therapy) can help reduce anxiety in adolescents (ages 11-18) who have Sickle Cell Disease. The researchers want to see if creating and playing songs is practical, acceptable, and helpful for managing anxiety. They will measure changes in anxiety and resilience scores over three months to see if the intervention is successful. You may be able to join if you are an adolescent with any type of sickle cell disease, receive care at a pediatric center, and can read and write in English. The study plans to enroll 30 participants, but its current status is unclear.

Study design
This is an interventional study planning to enroll 30 participants. It is not specified if it is randomized or blinded.
What's involved
Participants will engage in a songwriting intervention with a music therapist. Anxiety and resilience will be measured at the beginning of the study and again at 3 months.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 3 months after the start of the study.

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NCT07222475

Writing Relaxing Beats in Adolescents Who Have Sickle Cell Disease

Recruiting
NAAges 11–18InterventionalTreatment
Mayo Clinic
~30 participants
Updated 2026-02-23 on ClinicalTrials.gov
What's tested:Songwriting intervention (active music therapy)

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in State-Trait Anxiety Inventory score
Measured over Baseline, 3 months
+9 more outcomes measured

Conditions

Sickle Cell Disease

Explore related trials

Sickle Cell Disease

Where it's being run

1 sites across 1 states
Minnesota1

Study leadership

  • C. Robert Bennett, PhD · PRINCIPAL_INVESTIGATOR · Mayo Clinic

Who to contact

Pam Peterson
[email protected]
507-422-5523
Email the study team

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Eligibility criteria

Inclusion

Adolescents aged 11-18 years of age at the time of enrollment and able to provide assent
Diagnosed with any type of sickle cell disease
Currently receiving care at pediatric center
Able to read and write in English

Exclusion

Care transitioned to adult facility
Visual, hearing, or cognitive impairment which may impede the ability to complete the songwriting intervention or data collection measures

What this trial measures

  • Change in State-Trait Anxiety Inventory scoreBaseline, 3 months

    The State and Trait Anxiety Inventory measures anxiety. Participants respond to 20 questions about how they are currently feeling on a 4-point Likert scale of 1 (not at all) to 4 (very much so). A total score is calculated by summing the item responses and ranges from 20 to 80. Higher scores indicate higher anxiety (a worse outcome) and lower scores indicate less anxiety (a better outcome).

  • Change in Patient Health Questionnaire (PHQ-A) score Change in Patient Health Questionnaire for Adolescents (PHQ-A) scoreBaseline, 3 months

    The Patient Health Questionnaire for Adolescents (PHQ-A) is a modified version of the PHQ-9 to be used with adolescents. Participants respond to 9 questions scored on a 4-point Likert scale of 0 (Not at all) to 3 (Nearly every day). A total score is calculated by summing the item responses and ranges from 0 to 27; higher scores are associated with higher levels of or more severe depression.

  • Change in Connor Davidson Resilience Scale (CD-RISC 10) scoreBaseline, 3 months

    The Connor-Davidson Resilience scale (CD-RISC) measures resilience. Participants respond to 10 questions scored on a 5-point Likert scale of 0 (Not true at all) to 4 (True nearly all the time). A total score is calculated by summing the item responses and ranges from 0 to 40; with higher scores reflecting greater resilience.

  • Change in Difficulties in Emotion Regulation Scale (DERS-SF) scoreBaseline, 3 months

    The Difficulties in Emotion Regulation Scale Short Form (DERS-SF) measures difficulties in emotion regulation in adults and adolescents. It consists of six subscales: Nonacceptance, Goals, Impulse, Awareness, Strategies, and Clarity, each with three items. Participants respond to 18 questions scored on a 5-point Likert scale of 1 (Almost never) to 5 (Almost always). A total score is calculating by summing the item responses and ranges from 18 to 90; higher scores indicate greater difficulty with emotion regulation skills.

  • Change in PROMIS Pediatric Pain Behavior (SF-8a) scoreBaseline, 3 months

    The PROMIS Pediatric Pain Behavior (SF-8a) short form measures behaviors that typically indicate to others that an individual is experiencing pain. Participants respond to 8 questions scored on a 6-point Likert scale of 1 (Had no pain) to 6 (Almost always). A total score is calculated by summing the item responses and ranges from 8 to 48, with higher scores indicating a more pain related behavior.

  • Change in PROMIS Pediatric Pain Quality - Affective (SF-8a) scoreBaseline, 3 months

    The PROMIS Pediatric Pain Quality- Affective (SF-8a) short form assesses the emotional distress that accompanies pain. Participants respond to 8 yes or no questions (0 = no, 1 = yes). A total score is calculated by summing the item responses and ranges from 0 to 8, with higher scores indicating a greater impact of pain on emotional distress.

  • Change in PROMIS Pediatric Pain Quality - Sensory (SF-8a) scoreBaseline, 3 months

    The PROMIS Pediatric Pain Quality - Sensory (SF-8a) short form assesses the sensory experiences of pain. Participants respond to 8 questions scored on a 5-point Likert scale of 1 (Not at all) to 5 (Very much). A total score is calculated by summing the item responses and ranges from 8 to 40, with higher scores indicating participants experiencing increased sensory responses to pain.

  • Change in PROMIS Pediatric Physical Stress Experiences (SF-8a) scoreBaseline, 3 months

    The PROMIS Pediatric Physical Stress Experiences (SF-8a) short form assess the physically experienced sensations associated with pain. Participants respond to 8 questions scored on a 5-point Likert scale of 1 (Never) to 5 (Always). A total score is calculated by summing the item responses and ranges from 8 to 40, with higher scores indicating a greater impact of pain on physical stress experienced.

  • Change in PROMIS Pediatric Psychological Stress Experience (SF) scoreBaseline, 3 months

    The PROMIS Pediatric Psychological Stress Experience (SF) short form assesses the thoughts and feelings associated with pain. It measures facets of stress, including feeling overwhelmed, lack of perceived control, and cognitive-perceptual disruption, using a 7-day recall period. Participants respond to 8 questions scored on a 5-point Likert scale of 1 (Never) to 5 (Always). A total score is calculated by summing the item responses and ranges from 8 to 40, with higher scores indicating a greater impact of pain on psychological stress.

  • Change in PROMIS Pediatric Physical Activity (SF) scoreBaseline, 3 months

    The PROMIS Pediatric Physical Activity (SF) measure self-reported capability of physical activities. Participants respond to 8 questions scored on a 5-point Likert scale of 0 (No days) to 5 (6-7 days). A total score is calculated by summing item responses and ranges from 0 to 40, with higher scores indicating a greater deal of physical activity.