REVASC-PAD: Exercise for Peripheral Arterial Disease
This study, REVASC-PAD, is looking at how different types of exercise affect people with Peripheral Arterial Disease (PAD). PAD is a condition where narrowed arteries reduce blood flow to your limbs. We are testing a method called Blood Flow Restriction (BFR) training, which uses a cuff during exercise, against two other exercise methods: low-load resistance training and high-load resistance training. We want to see if BFR training can improve your walking ability and quality of life, and if it is safe. We are looking for 81 adults aged 18 or older who have been diagnosed with PAD and have stable leg pain (claudication). Your ankle-brachial index (ABI), a measure of blood flow, should be between 0.4 and 0.9. The study aims to see how your walking function and quality of life change over time with these exercises.
- Study design
- This is an interventional study with a planned enrollment of 81 participants. It compares three different exercise interventions.
- What's involved
- You would participate in exercise sessions, which include seated and standing calf raises. Your walking function and quality of life will be measured at the start, after 8-12 weeks of intervention, and again 3 months later.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for 3 months after the intervention period.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
REVASC-PAD: REstricted VASCular Exercise for Peripheral Arterial Disease - A Feasibility Study at University of Tennessee Medical Center
At a glance
Conditions
Where it's being run
1 sites across 1 statesWho to contact
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What this trial measures
- Walking FunctionBaseline (Visit 1), post-intervention (8 to 12 weeks), and 3-month follow-up (3MF)
Change in walking distance measured by the Six-Minute Walk Test (6MWT) from baseline to end of intervention and 3-month follow-up visit.
- Quality of Life (QoL) (1)Baseline (Visit 1), post-intervention (8 to 12 weeks), and 3-month follow-up (3MF)
Change in health-related quality of life as assessed by EuroQol 5-Dimension 5-Level (EQ-5D-5L) from baseline to post-intervention and 3-month follow-up
- Quality of Life (QoL) (2)Baseline (Visit 1), post-intervention (8 to 12 weeks), and 3-month follow-up (3MF)
Change in depressive symptoms as assessed by Patient Health Questionnaire-9 (PHQ-9) from baseline to post-intervention and 3-month follow-up
- Quality of Life (QoL) (3)Baseline (Visit 1), post-intervention (8 to 12 weeks), and 3-month follow-up (3MF)
Change in self-reported walking function and symptom burden assessed by using REVASC-PAD Walking Questionnaire from baseline to post-intervention and 3-month follow-up