Ketone Supplements and Carbohydrates for Cycling Performance

This study is looking at whether a drink containing a ketone supplement called R-1,3-Butanediol along with carbohydrates can help highly trained cyclists cycle longer before getting tired, compared to a drink with only carbohydrates. Researchers want to see if this combination increases the time you can cycle and if it leads to lower levels of lactate (a substance that builds up in your muscles during exercise) in your blood. You might be able to join if you are a healthy male or female cyclist between 18 and 55 years old, train at least six hours a week, and do not have certain health conditions like heart or lung disease. The study plans to enroll 15 participants and is currently unclear on its recruitment status.

Study design
This is an interventional study, meaning participants will receive specific treatments. It aims to enroll 15 highly trained cyclists.
What's involved
You will have three visits, each lasting about one hour and spaced at least 7 days apart. These visits will include a maximal cycling exercise test, finger pricks for blood samples, and wearing a mask to measure your breath.
Compensation
Not stated in the trial record.
Follow-up
Your time to fatigue will be measured through study completion, which is an average of 2 weeks.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07224282

The Effects of Ketone Supplements With Carbohydrates on Cycling Performance Above Lactate Threshold

Not Yet Recruiting
EARLY_PHASE1Ages 18–55InterventionalBasic science
University of Oklahoma
~15 participants
Updated 2025-11-04 on ClinicalTrials.gov
What's tested:Ketone supplementationCarbohydrate

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Time to fatigue
Measured over Through study completion, an average of 2 weeks.
Exogenous Ketosis

NCT07224282

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • University of Oklahoma

    Norman, Oklahomastudy coordinator listed

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Opens a ready-to-send draft in your own email app — review before sending.

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Eligibility criteria

Inclusion

Highly trained males and females
Ages 18-55
Greater than or equal to six hours of cycling training per week
Participants from the University of Oklahoma, Oklahoma cycling teams, and local cycling races in Oklahoma.

Exclusion

Cardiovascular disease
Respiratory disease
Gastrointestinal disease
Metabolic disease
Kidney disease
Neurological disease
Pregnancy
  • Time to fatigueThrough study completion, an average of 2 weeks.