Exercise and Mortality in Middle-Aged and Older Adults

This study is looking at how exercise habits affect how long people live (overall survival) and what causes their death (cause-specific mortality). Researchers are using information from a past study, the PLCO screening trial, which included over 150,000 adults aged 55 to 74. They are comparing people who reported little to no exercise with those who exercised at least two days a week for 20 minutes or more. The goal is to understand the link between self-reported exercise and health outcomes in middle-aged and older adults. This is an observational study, meaning researchers are looking at existing data rather than giving new treatments. The study is currently unclear on its status and aims to include 19,000 participants.

Study design
This is an observational study using existing data from a large group of participants. It is not a randomized trial where people receive different treatments.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants' health outcomes, including overall survival and cause-specific mortality, will be tracked for up to 19 years.

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NCT07224659

Exercise and Mortality in Middle-Aged and Older Adults

Not Yet Recruiting
Not specifiedAges 55–74Observational
City of Hope Medical Center
~19,000 participants
Updated 2026-08-19 on ClinicalTrials.gov
What's tested:ControlExercise

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Overall survival (all-cause mortality)
Measured over up to 19 years
+1 more outcome measured
Overall Survival (All-cause Mortality)
1 sites across 1 states
California1

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  • Overall survival (all-cause mortality)up to 19 years

    All-cause mortality (death from any cause) occurring within the follow-up period in the PLCO screening trial.

  • Cause-specific mortalityup to 19 years

    Cause-specific mortality (cancer mortality, mortality from other causes) occurring within the total follow-up period in the PLCO screening trial.