PIONEER Study: Silk Vista Baby Flow Diverters for Unruptured Intracranial Aneurysms

This study, called PIONEER, is testing a device called the Silk Vista Baby (SVB) Flow Diverter. This device is used to treat unruptured intracranial aneurysms (a weak, bulging spot in a blood vessel in the brain that hasn't burst yet). The study aims to see how safe and effective the SVB Flow Diverter is for adults aged 22 to 80 who have certain types of unruptured aneurysms. Success in this study means that the aneurysm is completely closed off one year after the procedure, without significant narrowing of the main artery or needing another treatment. The current status of this study is unclear, and it plans to enroll 250 participants.

Study design
This is a pivotal, multi-center, prospective, single-arm study, meaning all participants receive the same treatment. It plans to enroll 250 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for at least one year after the procedure to check for complete aneurysm closure.

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NCT07225075

Pivotal Study of the Silk Vista Baby Flow Diverters in the Treatment of Unruptured Intracranial Aneurysms (PIONEER)

Recruiting
NAAges 22–80InterventionalTreatment
Balt USA
~250 participants
Updated 2026-07-17 on ClinicalTrials.gov
What's tested:Silk Vista Baby (SVB) Flow Diverter

At a glance

Recruiting sites
3 of 3 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Proportion of participants with complete occlusion of the treated IA based on the Raymond-Roy I classification without significant parent artery stenosis (>50%), as evaluated by an independent Core Lab, without retreatment of the target aneurysm
Measured over 1 year post procedure
Intracranial Aneurysm
3 sites across 3 states
California1
Florida1
Ontario1
  • Ricardo Hanel, MD. PhD · PRINCIPAL_INVESTIGATOR · Baptist Medical Center Jacksonville
  • Vitor M Pereira, MD, MSc · PRINCIPAL_INVESTIGATOR · St. Michael's Hospital/Unity Health

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  • Proportion of participants with complete occlusion of the treated IA based on the Raymond-Roy I classification without significant parent artery stenosis (>50%), as evaluated by an independent Core Lab, without retreatment of the target aneurysm1 year post procedure