Meaning-Centered Therapy for Mexican Adults With Advanced Cancer

This study is looking at a type of talk therapy called Meaning-Centered Psychotherapy for Latinos (MCP-L) for Mexican adults with advanced cancer, including breast, prostate, colorectal, and thyroid cancers. The goal is to see if MCP-L can help reduce feelings of anxiety and depression and improve your quality of life. Researchers will compare MCP-L to another type of talk therapy called cognitive behavioral therapy (CBT). They also want to understand what participants and providers think about MCP-L. You may be able to join if you are an adult with one of these advanced cancers. The study aims to enroll 300 people.

Study design
This is an interventional study. It plans to enroll 300 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Your anxiety and depression levels will be measured at 1 month and 3 months after starting the therapy.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07225309

A Study of Meaning-Centered Therapy for Mexican Adults With Advanced Cancer

Recruiting
NAAges 18+InterventionalSupportive care
Memorial Sloan Kettering Cancer Center
~300 participants
Updated 2026-08-03 on ClinicalTrials.gov
What's tested:Meaning-Centered Psychotherapy for Latinos /MCP-L

At a glance

Recruiting sites
1 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in clinical levels of anxiety and depression for participants participating in Meaning-Centered Psychotherapy for Latinos (MCP-L)
Measured over 1 month
+1 more outcome measured
Breast Cancer
Prostate Cancer
Colorectal Cancer
Thyroid Cancer
Breast Cancer Stage III
Breast Cancer Stage IV
Prostate Cancer Stage III
Prostate Cancer Stage IV
Colorectal Cancer Stage III
Colorectal Cancer Stage IV
Thyroid Cancer Stage III
Thyroid Cancer Stage IV
2 sites across 2 states
New York1
Mexico1
  • Devika Jutagir, PhD · PRINCIPAL_INVESTIGATOR · Memorial Sloan Kettering Cancer Center

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Pathologically confirmed breast, prostate, colorectal, thyroid, cervix, uteri, or lung - solid tumor cancer (either most recent or new diagnosis)
Definition of Disease \[or Measurable Disease\]
Diagnosed with stages III or IV
Prior Treatment
Receiving ambulatory care at INCan
Age ≥ 18 years
Able to read and communicate in Spanish determined by the question: "Can you read and communicate in Spanish? Yes/No"
Professional role of administrators, clinicians (e.g., oncologists), mental health providers, supervised therapists-in-training (e.g., graduate students), or other related provider delivering the MCP-L experimental intervention
Providing care (or services) to Mexican cancer patients at INCan
Has access to internet and an electronic device
Agrees to be audio-recorded
Age ≥ 18 years
Able to read and communicate in Spanish determined by the question: "Can you read and communicate in Spanish? Yes/No"
Professional role of administrators, clinicians (e.g., oncologists), mental health providers, supervised therapists-in-training (e.g., graduate students), or other related provider delivering the MCP-L experimental intervention
Providing care (or services) to Mexican cancer patients at INCan
Has access to internet and an electronic device
Agrees to be audio-recorded

Exclusion

Prior Treatment
Received psychological or psychiatric care at INCan in the last 3 months
In the judgment of the treating physician, protocol investigators, and/or study staff, presence of cognitive impairment (e.g., delirium or dementia) sufficient to preclude meaningful informed consent and/or study participation
Diagnosed with a serious psychiatric condition
Received psychological or psychiatric care outside of INCan in the last 3 months
Presence of suicide risk determined by the Columbia-Suicide Severity Rating Scale
Too ill to participate determined by the question: "Do you feel too ill to participate because of communication problems, uncontrollable pain, or other symptoms that prevent you from participating?"
  • Change in clinical levels of anxiety and depression for participants participating in Meaning-Centered Psychotherapy for Latinos (MCP-L)1 month

    To examine the efficacy of Meaning-Centered Psychotherapy for Latinos (MCP-L) in improving clinical levels of anxiety and depression at 1-month post-intervention follow-up. Assessed using the General Anxiety Disorder 7-item scale (GAD-7; range 0-21, higher scores indicate greater anxiety levels) and the Patient Health Questionnaire 9-item scale (PHQ-9; range 0-27, higher scores indicate greater depression levels), respectively.

  • Change in clinical levels of anxiety and depression for participants participating in Meaning-Centered Psychotherapy for Latinos (MCP-L)3 months

    To examine the efficacy of Meaning-Centered Psychotherapy for Latinos (MCP-L) in improving clinical levels of anxiety and depression at 3-month post-intervention follow-up. Assessed using the General Anxiety Disorder 7-item scale (GAD-7; range 0-21, higher scores indicate greater anxiety levels) and the Patient Health Questionnaire 9-item scale (PHQ-9; range 0-27, higher scores indicate greater depression levels), respectively.