Spine Oncology Registry for Patients with Spine Tumors

This is an observational study, meaning it collects information about patients who are already receiving a specific treatment, rather than testing a new one. It's for adults (18 years or older) with primary or metastatic (spread from another part of the body) spine tumors who have surgery to decompress and stabilize the spine, followed by radiation therapy. The study aims to understand how well patients do after this treatment, looking at how long they live (overall survival) and if the tumor stays controlled in the treated area (local control). Researchers will also track how long patients live without their disease getting worse (progression-free survival). The study plans to include about 3000 participants. The current recruitment status is unclear.

Study design
This is an observational study, not testing a new intervention, and plans to enroll 3000 participants. It collects information from patients undergoing a specific treatment sequence.
What's involved
You will be asked to complete some patient-reported outcome questionnaires. Researchers will also collect information from your medical records.
Compensation
Not stated in the trial record.
Follow-up
Your overall survival will be measured at 12, 18, and 24 months. Local control and progression-free survival will be measured at various time points up to 24 months.

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NCT07225491

Spine Oncology Registry

Recruiting
Not specifiedAges 18+Observational
Ohio State University Comprehensive Cancer Center
~3,000 participants
Updated 2026-08-18 on ClinicalTrials.gov

At a glance

Recruiting sites
3 of 5 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Overall survival
Measured over 12, 18, 24 months
+2 more outcomes measured
Spine Tumor
Spine Metastases
Spine Cancer
5 sites across 5 states
Indiana1
Maryland1
Michigan1
New Jersey1
Ohio1
  • James B Elder, MD · PRINCIPAL_INVESTIGATOR · Ohio State University

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Eligibility criteria

Inclusion

Diagnosis of primary or metastatic disease to the spine who undergo surgical decompression and stabilization followed by radiation therapy

Exclusion

Inability to obtain a standard MRI or CT / CT myelogram for radiation treatment planning and dosimetry
Inability to receive radiation treatment.
Patients under 18 years of age
  • Overall survival12, 18, 24 months
  • Local control of treated lesion based on radiographic review3, 6, 9, 12, 15, 16, 21, 24 months

    Patients will be classified as achieving local control if demonstrating response of treated spine lesion after treatment. Local control will be assessed by comparing the radiographic images after treatment and prospectively every 3 months for up to 24 months

  • Progression free survival3, 6, 9, 12, 15, 16, 21, 24 months