Comparing Weekly Somatrogon to Daily Genotropin for Short Stature
This study is looking at two growth hormone treatments for children with short stature. It compares a once-weekly injection called Somatrogon to a daily injection called Genotropin. We want to see if Somatrogon works as well as Genotropin and if it's safe. Children who can join are between 3 and 11 years old, have not yet started puberty, and have short stature because they were born small for their gestational age (SGA) or have idiopathic short stature (ISS), meaning the cause of their short stature isn't known. The main goal is to see how much children grow in height over 12 months. The study is currently recruiting participants.
- Study design
- This is an open-label study, meaning you and your doctor will know which treatment you are receiving. It will involve about 254 children who will be randomly assigned to receive either Somatrogon or Genotropin.
- What's involved
- Participants will receive treatment for 12 months, with a screening period of up to 30 days before starting treatment.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary endpoint, annual height velocity, is measured after 12 months of treatment.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Comparison of Weekly Somatrogon to Daily Genotropin in Children Born Small for Gestational Age or With Idiopathic Short Stature.
At a glance
Conditions
NCT07226089
Where you'd take part
This study runs at 32 sites. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
All India Institute of Medical Sciences (AIIMS) - New Delhi
New Delhi, Indiastudy coordinator listed
Not yet recruiting
Apollo Hospitals Enterprise Limited
Navi Mumbai, Indiastudy coordinator listed
Not yet recruiting
Assaf Harofe Medical Center
Rishon LeZiyyon, Israelstudy coordinator listed
Not yet recruiting
Atlantic Health System
Morristown, New Jerseystudy coordinator listed
Not yet recruiting
Centre Hospitalier Universitaire d'Angers
Angers, Francestudy coordinator listed
Not yet recruiting
Children's Minnesota - Minneapolis
Minneapolis, Minnesotastudy coordinator listed
Not yet recruiting
Chu de Lyon - Hopital Femme Mere Enfant
Lyon, Francestudy coordinator listed
Not yet recruiting
CHU Hôpital de la Timone
Marseille, Francestudy coordinator listed
Not yet recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- Moshe Phillip, Professor · STUDY_DIRECTOR · Schneider Children's Medical Center
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- Annual Height Velocity• Annualized HV after 12 months of treatment
Annual Height Velocity in cm. Annual Height Velocity at 12 months is based on the difference between the heights at 12 months and baseline.