SL1002 for Osteoarthritis Knee Pain

This study is testing an injectable solution called SL1002 to see if it can safely and effectively reduce knee pain caused by osteoarthritis. You might be able to join if you are at least 40 years old, have chronic knee pain from mild to moderate osteoarthritis, and meet other health requirements like certain Body Mass Index (BMI) limits. The researchers will compare SL1002 to normal saline (a placebo) to see if SL1002 helps reduce your average daily pain intensity while walking over 12 weeks. The study aims to enroll 150 participants, but its current recruitment status is unclear.

Study design
This is a randomized, double-blind, placebo-controlled study, meaning participants are randomly assigned to receive either SL1002 or normal saline, and neither you nor your doctor will know which you are receiving. It is designed to assess the safety and effectiveness of a single dose.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The main goal is to measure changes in pain from when you start the study until Week 12.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07226258

Phase III Study to Assess the Safety and Efficacy of SL1002 for Osteoarthritis Knee Pain

Recruiting
PHASE3Ages 40+InterventionalTreatment
Saol Therapeutics Inc
~150 participants
Updated 2026-08-25 on ClinicalTrials.gov
What's tested:SL1002Normal Saline

At a glance

Recruiting sites
22 of 22 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change From Baseline to Week 12 in the Weekly Mean of the Average Daily Pain Intensity While Walking
Measured over Baseline to week 12
Osteoarthritis Knee Pain
22 sites across 13 states
Florida4
Texas3
California2
North Carolina2
Pennsylvania2
South Carolina2
Colorado1
District of Columbia1

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  • Change From Baseline to Week 12 in the Weekly Mean of the Average Daily Pain Intensity While WalkingBaseline to week 12

    The pain intensity score is measured using a numeric rating scale (NRS)