The HEAT Study: Hysterosalpingogram (HSG) Experience and Tubal Spasm

This study, called The HEAT Study, is looking at ways to make the hysterosalpingogram (HSG) procedure more comfortable for women experiencing infertility. An HSG is an X-ray test that checks if your fallopian tubes are open. Sometimes, the dye used in the HSG can cause cramping and make it seem like your tubes are blocked when they aren't. This study will compare using warmed HSG contrast (dye) versus room temperature contrast to see if warmed contrast reduces pain. We are looking for women aged 18-45 who are having an HSG as part of their fertility evaluation. The main goal is to measure your pain level one hour after the HSG procedure. This study is currently recruiting about 240 participants.

Study design
This is an interventional study where participants will be randomly assigned to receive either warmed or room temperature HSG contrast. Approximately 240 women are planned to participate.
What's involved
You would undergo an HSG procedure, and your medical history will be collected. You will also complete a pain questionnaire one hour after the procedure.
Compensation
Not stated in the trial record.
Follow-up
Your pain will be measured one hour after the HSG procedure.

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NCT07226310

The Hysterosalpingogram (HSG) Experience And Tubal Spasm (HEAT) Study

Recruiting
EARLY_PHASE1Ages 18–45InterventionalPrevention
University of Oklahoma
~240 participants
Updated 2026-07-30 on ClinicalTrials.gov
What's tested:Warmed HSG

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Post-HSG Pain Questionnaire
Measured over Measured 1 hour after HSG procedure
Infertility
1 sites across 1 states
Oklahoma1
  • LaTasha Craig, MD · PRINCIPAL_INVESTIGATOR · University of Oklahoma Health Center

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  • Post-HSG Pain QuestionnaireMeasured 1 hour after HSG procedure

    To compare the patient experience for patients undergoing HSG when warm versus cold contrast media is utilized, patients will complete a post-HSG Questionnaire to indicate their level of pain.