A Study of LY4584180 in Adult Participants With Previously Treated Blood Cancers
This study is testing a new oral medication called LY4584180, sometimes given with Rituximab (an IV infusion), for adults with certain blood cancers like Lymphoma, Non-Hodgkin's, Diffuse Large B-Cell Lymphoma, and Follicular Lymphoma. You may be able to join if you've already had at least two other treatments for your blood cancer or can't receive other available therapies. Researchers want to see how safe LY4584180 is, how well it works to shrink tumors, and how your body processes the medication. The study will track side effects and how many participants respond to the treatment. The status of this study is currently unclear.
- Study design
- This is an interventional study planning to enroll 460 participants. The phase of the study is not specified.
- What's involved
- The study could last about 9 months or possibly longer, including an initial screening period. Specific details about visits, procedures, or tests are not provided.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be monitored for serious side effects for up to 3 years. Tumor response will also be evaluated for up to 3 years.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
A Study of LY4584180 in Adult Participants With Previously Treated Blood Cancers
At a glance
Conditions
Where it's being run
46 sites across 21 statesStudy leadership
- Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 8 AM - 8 PM Eastern time (UTC/GMT - 5 hours, EST) · STUDY_DIRECTOR · Eli Lilly and Company
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
Do you actually qualify for this trial?
Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.
Inclusion
Exclusion
What this trial measures
- Number of Dose-Limiting Toxicities (DLTs) and DLT-Equivalent ToxicitiesBaseline up to Day 28
Number of Dose-Limiting Toxicities (DLTs) and DLT-Equivalent Toxicities
- Number of Participants with One or More Serious Adverse Events (SAEs) Considered by the Investigator to be Related to Study Drug AdministrationBaseline up to 3 Years
Number of Participants with One or More Serious Adverse Events (SAEs) Considered by the Investigator to be Related to Study Drug Administration
- To Evaluate the Preliminary Antitumor Activity of LY4584180: Objective Response Rate (ORR)Baseline up to 3 Years
To Evaluate the Preliminary Antitumor Activity of LY4584180: Objective Response Rate (ORR)