Understanding Blood Pressure Responses in Type 2 Diabetes
This study is looking at why people with Type 2 Diabetes (T2DM) sometimes have high blood pressure during exercise, which can increase their risk of heart problems. Researchers want to see if issues with blood vessel function and cell damage are causing these high blood pressure responses. You might be eligible if you are 18-80 years old and have Type 2 Diabetes or are a healthy control. Participants will receive either an over-the-counter antioxidant supplement called MitoQ or a placebo (an inactive substance) to see how it affects blood flow and muscle function. The main goal is to measure changes in your blood pressure and heart rate before and 45 minutes after taking the supplement. The study is currently unclear on its recruitment status and plans to enroll 40 people.
- Study design
- This is an interventional study planning to enroll 40 participants, including individuals with Type 2 Diabetes and healthy controls. Participants will receive either MitoQ or a placebo.
- What's involved
- During each testing session, you will orally take either MitoQ or a placebo. Researchers will measure your blood pressure and heart rate before and 45 minutes after taking the supplement.
- Compensation
- Not stated in the trial record.
- Follow-up
- Measurements for primary endpoints (blood pressure and heart rate) are taken prior to and 45 minutes following supplement administration.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Role of Endothelial Dysfunction on Exercise Pressor Reflex in Type 2 Diabetes
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- William E Hughes, Ph.D. · PRINCIPAL_INVESTIGATOR · Medical College of Wisconsin
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Mean Arterial PressurePrior to and 45 minutes following supplement
Change in mean arterial pressure is measured in response to handgrip exercise and post-exercise circulatory occlusion
- Heart RatePrior to and 45 minutes following supplement
Change in heart rate is measured in response to handgrip exercise and post-exercise circulatory occlusion