Study of ABBV-142 for Idiopathic Pulmonary Fibrosis

This study is looking into a new treatment, ABBV-142, for adults with Idiopathic Pulmonary Fibrosis (IPF). IPF is a rare lung disease that causes scarring and breathing difficulties. The study aims to see how safe ABBV-142 is, how well people tolerate it (meaning how well they can handle any side effects), and if it helps improve lung function. You might be able to join if you've been diagnosed with IPF within the last seven years, and your diagnosis is confirmed by a recent chest scan. The study will compare ABBV-142 to a placebo (an inactive substance). Researchers will measure changes in your lung capacity (Forced Vital Capacity or FVC) after 24 weeks and track any side effects for up to about 52 weeks. The study plans to enroll 165 participants, but its current recruitment status is unclear.

Study design
This is an interventional study with an estimated enrollment of 165 participants. It is a platform study, meaning it can evaluate different treatments over time.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants will be monitored for adverse events for up to approximately 52 weeks.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07230288

Study of ABBV-142 to Assess Adverse Events and Change in Disease Activity in Adult Participants With Idiopathic Pulmonary Fibrosis

Recruiting
PHASE2Ages 40+InterventionalTreatment
AbbVie
~165 participants
Updated 2026-09-03 on ClinicalTrials.gov
What's tested:ABBV-142Placebo for ABBV-142

At a glance

Recruiting sites
57 of 57 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Absolute Change From Baseline in Forced Vital Capacity (FVC) (mL)
Measured over Week 24
+1 more outcome measured
Idiopathic Pulmonary Fibrosis

NCT07230288

Where you'd take part

This study runs at 57 sites. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Acibadem City Clinic Tokuda University Hospital EAD /ID# 277846

    Sofia, Bulgariano site contact published

    Recruiting

  • Caritas-Krankenhaus St. Maria gGmbH /ID# 278138

    Donaustauf, Bavaria, Germanyno site contact published

    Recruiting

  • Centre d'Investigation Clinique Mauricie /ID# 277949

    Trois-Rivières, Quebec, Canadano site contact published

    Recruiting

  • Centre Hospitalier Universitaire de Rennes - Hopital Pontchaillou /ID# 278333

    Rennes, Ille-et-Vilaine, Franceno site contact published

    Recruiting

  • China Medical University Hospital /ID# 278039

    Taichung, Taiwanno site contact published

    Recruiting

  • Christie Clinic on University /ID# 277871

    Champaign, Illinoisno site contact published

    Recruiting

  • Clinical Research Specialists - Kissimmee /ID# 279184

    Kissimmee, Floridano site contact published

    Recruiting

  • Diagnostic Consultative Center Convex /ID# 277848

    Sofia, Bulgariano site contact published

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • ABBVIE INC. · STUDY_DIRECTOR · AbbVie

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Eligibility criteria

Exclusion

History of stroke within 6 months prior to screening
In the opinion of the investigator, other clinically significant pulmonary abnormalities
History of any malignancy up to 5 years prior screening visit, except for successfully treated nonmelanoma skin cancer or localized carcinoma in situ of the cervix.
  • Absolute Change From Baseline in Forced Vital Capacity (FVC) (mL)Week 24

    FVC is a test that measures the total amount of air a person can fully exhale from their lungs after a deep inhalation. A low FVC can demonstrate reduced lung capacity.

  • Percentage of Participants with Adverse Events (AE)Up to approximately 52 weeks

    An adverse event (AE) is defined as any untoward medical occurrence in a participant or clinical investigation participant administered a pharmaceutical product which does not necessarily have a causal relationship with the treatment. The investigator assesses the relationship of each event to the use of study drug.