The RADIANCE CED Study: Ultrasound Renal Denervation for Uncontrolled High Blood Pressure

The RADIANCE CED study is looking at the long-term effects of a treatment called Ultrasound Renal Denervation (using the Paradise™ Ultrasound Renal Denervation (uRDN) System) on blood pressure. This treatment uses ultrasound energy to target nerves in the kidneys that can contribute to high blood pressure. The study wants to see if this treatment helps lower blood pressure in people with uncontrolled high blood pressure (hypertension). You might be able to join if you are 65 or older, have uncontrolled high blood pressure, and are already taking stable blood pressure medication. You cannot join if your high blood pressure is due to other conditions, you've had this treatment before, are pregnant, or have severe kidney disease. The study will measure changes in blood pressure between November 2025 and December 2029. The current status of the study is unclear.

Study design
This is an observational study, meaning researchers will collect information from existing health records of Medicare-eligible patients. It aims to include 1000 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Blood pressure changes will be assessed between November 2025 and December 2029.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07231757

The RADIANCE CED Study

Recruiting
Not specifiedAges 65+Observational
ReCor Medical, Inc.
~1,000 participants
Updated 2026-07-16 on ClinicalTrials.gov
What's tested:Ultrasound Renal Denervation (Paradise™ Ultrasound Renal Denervation (uRDN) System)

At a glance

Recruiting sites
2 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Assessment for Changes in Blood Pressure
Measured over November 2025 - December 2029
Hypertension
Cardiovascular Diseases
Vascular Diseases
2 sites across 1 states
Michigan2
  • Megan Coylewright, MD · PRINCIPAL_INVESTIGATOR · Essentia Health
  • Amir Kaki, MD · PRINCIPAL_INVESTIGATOR · Ascension St. John Hospital

Opens a ready-to-send draft in your own email app — review before sending.

Do you actually qualify for this trial?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

Adults aged ≥65 years with uncontrolled hypertension
Stable regimen of blood pressure-lowering medication

Exclusion

Hypertension due to secondary causes
Prior renal denervation treatment
Pregnancy
End-stage renal disease, dialysis, or kidney transplant
  • Assessment for Changes in Blood PressureNovember 2025 - December 2029