Algorithm Development for Restoring Movement After Paralysis

This study is developing new algorithms to help people with paralysis regain complex movement. You would participate in experiments where non-invasive sensors (like EEG, which measures brain waves, or EMG, which measures muscle activity) record your activity. You might be asked to imagine, try, or perform actions to control a computer, robotic arm, or wheelchair. The goal is to see how well these recorded signals can be used to guide these devices. We are looking for 50 healthy English-speaking adults aged 18 and older who do not have neurological injuries or diseases causing paralysis. Success will be measured by how well the algorithms perform.

Study design
This interventional study plans to enroll 50 healthy participants. It is not specified if it is randomized or blinded.
What's involved
You would typically have one study visit, with possible additional visits within a month. During these visits, you would wear sensors and perform, imagine, or attempt movements or speech.
Compensation
Not stated in the trial record.
Follow-up
Not specified.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07236892

Towards Restoring Complex Movement After Paralysis: Algorithm Development With Healthy Participants

Recruiting
NAAges 18+InterventionalBasic science
University of California, Los Angeles
~50 participants
Updated 2025-12-24 on ClinicalTrials.gov
What's tested:Participants will perform experimental tasks while undergoing non-invasive activity recordings, which may include EEG, EMG, IMUs, fNIRS, eye gaze, or pupillometry.

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Normalized Performance
Measured over Usually one visit (Day 1), with possible additional study visits usually within a month.
Movement Disorders
Neurorehabilitation
Non-invasive Activity Recording
1 sites across 1 states
California1
  • Jonathan Kao, PhD · PRINCIPAL_INVESTIGATOR · UCLA Neural Engineering and Computation Lab
Restoring Movement Study Coordinator
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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Fluent in the English language

Exclusion

Neurological injury or disease that results in functional paralysis
  • Normalized PerformanceUsually one visit (Day 1), with possible additional study visits usually within a month.

    The normalized performance of the non-invasive assistive interface on a task. Non-invasive signals, which may include electroencephalography, electromyography, functional near infrared spectroscopy, inertial measurements units, eye movements, pupil size, and speech are input into an algorithm that controls an end effector's movements. The end effector, which may be a computer cursor, robotic manipulator, wheelchair, or other assistive device, is used to perform a motor task. The normalized performance is derived from the the performance of the end effector on the motor task, reflecting the overall performance of the non-invasive assistive interface. The minimum value is zero. There is no maximum value, although the values are usually less than 1. Higher is better.