Minocycline in Stroke Study at Maimonides
This study at Maimonides aims to see if adding Minocycline, a common antibiotic, to standard stroke care can help patients recover better after a stroke. Researchers want to find out if Minocycline improves stroke severity (measured by the National Institutes of Health Stroke Scale or NIHSS) and reduces disability or death for people who have had either an ischemic or hemorrhagic stroke. You might be able to join if you are 18 or older and have had a moderate stroke within the last 24 hours. The study is looking for 1,164 participants, but its current recruitment status is unclear.
- Study design
- This study will involve 1,164 adults and will randomly assign participants to receive either Minocycline plus standard stroke care, or standard stroke care alone.
- What's involved
- If you participate, you would receive Minocycline 200 mg once daily for five days, initiated within 24 hours of your stroke. Your stroke severity and disability will be measured at hospital discharge, 30 days, and 90 days.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for changes in stroke severity at 7 days and 90 days after stroke onset.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Minocycline in Stroke Study at Maimonides
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Qingliang T. Wang, MD, PhD · PRINCIPAL_INVESTIGATOR · Maimonides Medical Center
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- Change in National Institutes of Health Stroke Scale (NIHSS) Score at Day 7 post strokeAt day 7 after stroke onset
The NIHSS score will be assessed at Day 7 post-stroke to measure neurological impairment and recovery. The primary outcome is the difference in NIHSS scores between the Minocycline plus standard care group and the standard care alone group.
- Change in National Institutes of Health Stroke Scale (NIHSS) Score at 90 days (+/- 7 days) post-strokeAt 90 days (+/- 7 days) after stroke onset
The NIHSS score will be assessed 90 days (+/- 7 days) post-stroke to measure neurological impairment and recovery. The primary outcome is the difference in NIHSS scores between the Minocycline plus standard care group and the standard care alone group.