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Digital Tool for Exercise Prescriptions in Cardiovascular Disease Risk

This study is testing a new digital tool called P3-EX that helps doctors prescribe exercise to patients who have risk factors for heart disease, such as high blood pressure (hypertension), high cholesterol (dyslipidemia), diabetes, or obesity. You would participate in a 12-week unsupervised exercise program with virtual weekly check-ins from research assistants. The study wants to see if P3-EX is easy for doctors to use and if patients find it helpful. They are also comparing it to another exercise program called ACSM-PAVS. The study is looking for 72 participants between 18 and 64 years old. The current recruitment status is unclear.

Study design
This is a randomized controlled trial involving 72 participants. Doctors will recruit two patients each, with one receiving the P3-EX exercise prescription and the other receiving the ACSM-PAVS exercise prescription.
What's involved
You would follow a 12-week unsupervised exercise program. You would also have virtual weekly oversight from graduate research assistants.
Compensation
Not stated in the trial record.
Follow-up
The main study goals (feasibility and acceptability) are measured within 48 hours after the exercise programs are delivered.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07238556

A Novel Digital Tool Physicians Can Use to Prescribe Exercise to Patients With Cardiovascular Disease Risk Factors

Recruiting
NAAges 18–64InterventionalHealth services
University of Connecticut
~72 participants
Updated 2026-08-12 on ClinicalTrials.gov
What's tested:Experimental - 12 Week P3-EX Unsupervised Exercise Program with Virtual Weekly Oversight from Graduate Research AssistantsActive Control - 12 Week ACSM-PAVS Unsupervised Exercise Program with Virtual Weekly Oversight from Graduate Research Assistants

At a glance

Recruiting sites
2 of 3 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Feasibility and Acceptability of Prioritize Personalize Prescribe EXercise (P3-EX)
Measured over Within 48 hours following the delivery of P3-EX and ACSM-PAVS
+1 more outcome measured

Conditions

Hypertension
Dyslipidemia
Diabetes Mellitus
Obesity
Cardiovascular Disease

Explore related trials

Cardiovascular DisorderDiabetes MellitusDyslipidemiaHypertensionObesity

Where it's being run

3 sites across 1 states
Connecticut3

Study leadership

  • Linda S Pescatello, PhD · PRINCIPAL_INVESTIGATOR · Department of Kinesiology, University of Connecticut
  • Antonio B Fernandez, MD · PRINCIPAL_INVESTIGATOR · Hartford HealthCare Heart & Vascular Institute, Hartford Hospital
  • Gregory Panza, PhD · STUDY_DIRECTOR · Department of Research Administration, Hartford HealthCare

Who to contact

Alexander J Wright, MS
[email protected]
(860) 486-6814
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Obesity: BMI ≥30 kg/m2 or WC \>102 cm (40 in) for men and \>88 cm (35 in) for women
Hypertension: Systolic BP ≥130 mm Hg and/or diastolic BP ≥80 mm Hg, or on antihypertensive medication
Dyslipidemia: LDL-C ≥130 mg/dL (3.37 mmol/L), or HDL-C \<40 mg/dL (1.04 mmol/L) in men and \<50 mg/dL (1.3 mmol/L) in women, or non-HDL-C ≥160 mg/dL (4.14 mmol/L), or on lipid-lowering medication, or TC ≥200 mg/dL (5.18 mmol/L)
Diabetes (or prediabetes): FBG ≥100 mg/dL or HbA1c ≥5.7%, or on medication for diabetes 4. Healthy: Having no signs or symptoms of or have cardiovascular or renal disease, or other diseases or health conditions that significantly limit physical activity engagement 5. Not pregnant or lactating 6. Not a cigarette smoker or quit smoking ≥6 months ago 7. Consume \<2 alcoholic drinks daily 8. Able to use a computer or phone with internet access 9. Fluent in English 10. Willing to maintain their medication routine and habitual diet and not follow other exercise or nutrition programs.

What this trial measures

  • Feasibility and Acceptability of Prioritize Personalize Prescribe EXercise (P3-EX)Within 48 hours following the delivery of P3-EX and ACSM-PAVS

    The mHealth Application Usability Questionnaire is validated to measure the usability of mobile health apps for healthcare providers and/or patients through 21 items spilt into three subscales; Ease of Use and Satisfaction, System Information Arrangement, and Usefulness. The rating of each item is scaled from 1 to 7, and responses are averaged to provide a single score. Physicians will rate both P3-EX and American College of Sports Medicine Physical Activity Vital Sign (ACSM-PAVS), and patients will rate the one they receive. Overall scores (mean ± SD) will be compared to the middle score of 4.0.

  • Feasibility and Acceptability of Prioritize Personalize Prescribe EXercise (P3-EX)Within 48 hours following the delivery of P3-EX and ACSM-PAVS

    The System Usability Scale is the most common questionnaire to assess the usability of mHealth apps. Ratings for each of the 10 items are scaled from 1 to 5. Physicians will rate both P3-EX and American College of Sports Medicine Physical Activity Vital Sign (ACSM-PAVS), and patients will rate the one they receive. Overall scores (mean ± SD) will be scaled from 0 to 100 and compared to normative reference ratings and scores in the literature.