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Cardiovascular Health for Childhood Cancer Survivors

This study, called "Evaluation Of Cardiovascular Health Outcomes Among Survivors 2," is for childhood cancer survivors who received certain treatments that put them at higher risk for heart problems. It's testing two different approaches to help you understand this risk and encourage you to get a recommended heart screening test (echocardiogram). One approach is a "Survivorship Care Plan + Educational Materials" delivered through an online platform. The other, called "Healthy Hearts eHealth Program," includes the same materials plus interactive online tools like avatar-led motivational interviewing. The study aims to see if the Healthy Hearts eHealth Program helps more people get their heart screening at 12 months compared to the standard educational materials. You can join if you are a Childhood Cancer Survivor Study (CCSS) participant, are 26 years or older, and meet specific treatment history and heart health criteria. The study is planning to enroll 350 participants, but its current status is unclear.

Study design
This interventional study will randomly assign participants to either receive standard educational materials or the Healthy Hearts eHealth Program. It plans to enroll 350 participants.
What's involved
You will complete a 15-20 minute survey at the beginning of the study. After that, you will receive either educational materials or an interactive eHealth program.
Compensation
Not stated in the trial record.
Follow-up
The study will measure outcomes at 12 months.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07245420

Evaluation Of Cardiovascular Health Outcomes Among Survivors 2

Recruiting
NAAges 26+Interventional
St. Jude Children's Research Hospital
~350 participants
Updated 2026-06-26 on ClinicalTrials.gov
What's tested:Survivorship Care Plan + Educational Materials (delivered via CIAS platform)Healthy Hearts eHealth Program

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Number of Participants who Received Cardiomyopathy Screening at 12 months between Participants Randomized to the Healthy Hearts eHealth Intervention group as compared to the standard of care.
Measured over 12 months
+1 more outcome measured

Conditions

Health Behavior

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Childhood Cancer Survivors

NCT07245420

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • St. Jude Children's Research Hospital

    Memphis, Tennesseestudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Study leadership

  • Matthew Ehrhardt, MD, MS, MPI · PRINCIPAL_INVESTIGATOR · St. Jude Children's Research Hospital

Who to contact

Matthew Ehrhardt, MD, MS, MPI
[email protected]
888-226-4343
Email the study team

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Eligibility criteria

Inclusion

Childhood Cancer Survivor Study (CCSS) Participants
Age ≥26 years
Treated with cumulative doxorubicin equivalent anthracycline doses ≥100 mg/m2 with any/no radiation, or ≥15 Gy chest radiation with any/no anthracyclines
No history of cardiomyopathy
Has not had an echocardiogram in the previous 5 years
Has a history of successful completion of CCSS surveys
English-Speaking
Has not been enrolled in ECHOS-1 (pilot)

What this trial measures

  • Number of Participants who Received Cardiomyopathy Screening at 12 months between Participants Randomized to the Healthy Hearts eHealth Intervention group as compared to the standard of care.12 months

    This outcome will be measured through self-reported questionnaire at 12 months along with confirmation through medical record review.

  • Difference in Precursors to Cardiomyopathy Screening at 12 months between Participants Randomized to the Healthy Hearts eHealth Intervention group as Compared to the Standard of Care.12 months

    This outcome will use questions included in the baseline and 12 month questionnaire to calculate the differences in precursors to cardiomyopathy screening (perceived barriers, knowledge, motivation, beliefs, self-efficacy) at 12 months between participants randomized to Healthy Hearts eHealth Intervention vs participants assigned to standard care.