Study on Pain Management for Penile Prosthesis Surgery

This study is looking at a way to manage pain after inflatable penile prosthesis (IPP) surgery for erectile dysfunction (ED). Researchers are testing a mixture of Exparel (a long-acting numbing medicine) and bupivacaine (another numbing medicine) given directly into the penis during surgery. The goal is to see if this mixture can reduce pain after the operation, potentially lessening the need for opioid pain medications. The study will measure your pain using a Visual Analogue Scale (VAS) at 1, 4, and 24 hours after surgery. You may be able to join if you are a man aged 21 or older who is having your first IPP surgery at Lexington Medical Center. We don't know the current recruitment status.

Study design
This is an interventional study with a planned enrollment of 100 participants. The study is exploring a new approach to pain management during surgery.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Your pain levels will be measured at 1, 4, and 24 hours after surgery.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07246642

IPP Placement & Intracavernosal Block

Not Yet Recruiting
PHASE4Ages 21+InterventionalTreatment
Wake Forest University Health Sciences
~100 participants
Updated 2026-05-26 on ClinicalTrials.gov
What's tested:Exparel/bupivacaine mixture

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Visual Analogue Scale (VAS) Scores
Measured over Hour 1
+2 more outcomes measured
Erectile Dysfunction (ED)
1 sites across 1 states
North Carolina1
  • Ryan Terlecki, MD · PRINCIPAL_INVESTIGATOR · Wake Forest University Health Sciences

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Eligibility criteria

Inclusion

Any patient undergoing primary three-piece inflatable penile prosthesis (IPP) placement at Lexington Medical Center

Exclusion

Patients undergoing revision and/or secondary IPP placement
Patients taking prescribed narcotic medications at the time of IPP surgery
Patients undergoing concomitant Peyronie's Disease surgery (modeling, plication, grafting) at the time of IPP surgery
Patients with liver and/or renal disease
  • Visual Analogue Scale (VAS) ScoresHour 1

    VAS scores range from 0 to 100, with 0 representing no pain or the least desirable state and 100 representing the worst possible pain or the most desirable state. The "score" is the distance in millimeters from the "no pain" end of the 100mm line to the point where the person marks their pain level. Lower scores (0-4mm) indicate no pain, while higher scores (75-100mm) indicate severe pain.

  • Visual Analogue Scale (VAS) ScoresHour 4

    VAS scores range from 0 to 100, with 0 representing no pain or the least desirable state and 100 representing the worst possible pain or the most desirable state. The "score" is the distance in millimeters from the "no pain" end of the 100mm line to the point where the person marks their pain level. Lower scores (0-4mm) indicate no pain, while higher scores (75-100mm) indicate severe pain.

  • Visual Analogue Scale (VAS) ScoresHour 24

    VAS scores range from 0 to 100, with 0 representing no pain or the least desirable state and 100 representing the worst possible pain or the most desirable state. The "score" is the distance in millimeters from the "no pain" end of the 100mm line to the point where the person marks their pain level. Lower scores (0-4mm) indicate no pain, while higher scores (75-100mm) indicate severe pain.