Self-Help Cognitive Processing Therapy (CPT) for Women Veterans with PTSD

This study is looking at new ways to help women veterans who have Posttraumatic Stress Disorder (PTSD) and depression. It tests two approaches: a self-help version of Cognitive Processing Therapy (CPT), which is a type of talk therapy proven to help with PTSD, and a combination of self-help CPT with support from the Women Veterans Network (WoVeN). You might be able to join if you are a woman veteran, aged 18 or older, and have a PTSD diagnosis. The study will measure how much your PTSD symptoms improve to see if these approaches are helpful. The current recruitment status is unclear, but the study plans to enroll 100 participants.

Study design
This is a randomized controlled study with three groups, involving 100 women veterans. Participants will be randomly assigned to receive self-help CPT, self-help CPT plus WoVeN support, or standard care.
What's involved
You would complete treatments within 10 weeks, and have three main assessments (at the start, after 10 weeks, and 3 months later) that take about 2.5 hours each. You would also complete weekly surveys to track your progress.
Compensation
Not stated in the trial record.
Follow-up
Your PTSD symptoms will be checked at 10 weeks (after treatment) and again at 28 weeks (about 3 months after treatment).

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NCT07250061

Self-Help Cognitive Processing Therapy (CPT)/Women Veterans Network (WoVeN) Study

Recruiting
NAAges 18+InterventionalTreatment
Boston University
~100 participants
Updated 2026-05-27 on ClinicalTrials.gov
What's tested:Self-Help Cognitive Processing TherapyWomen Veterans Network (WoVeN)Treatment as Usual

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Clinician assessed PTSD Symptoms
Measured over Pre intervention- baseline, Post intervention- 10 weeks, Follow-up- 28 weeks
Posttraumatic Stress Disorder
Depression
1 sites across 1 states
Massachusetts1
  • Tara E Galovski, PhD · PRINCIPAL_INVESTIGATOR · BUCA School of Medicine, Psychiatry and VA Medical Center

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Identifies as a woman
Has served in the United States military
A full or subthreshold (meets criteria for 2 out of 4 of the symptom clusters for PTSD) Post Traumatic Stress Disorder (PTSD) diagnosis
Able to read English well enough to complete study questionnaires

Exclusion

Clinician judgment that the participant is not appropriate for self-help level of care for PTSD (i.e., recent psychiatric hospitalization, requires detox, volatile, active suicidality)
Current psychosis or unstable bipolar disorder (determined during baseline interview as described in screening and enrollment procedures)
Must not have participated in a WoVeN group within the last year
Must not be receiving an evidenced-based therapy for PTSD at the time of the screening
  • Clinician assessed PTSD SymptomsPre intervention- baseline, Post intervention- 10 weeks, Follow-up- 28 weeks

    This outcome will be assessed with the Clinician-Administered PTSD Scale for the Diagnostic and Statistical Manual of Mental Illnesses (DSM-5) (CAPS-5). It obtains information about frequency and intensity for the 20 PTSD symptoms using a 5-point ordinal scale from 0 (absent) to 4 (extreme/incapacitating), based on the patient's frequency and intensity of the symptom. The final score is a total severity score that can range from 0 to 80 with higher scores indicating more severe PTSD symptoms.