This study is looking at new ways to use a common heart failure medicine called Furosemide (an intravenous solution, meaning it's given through a vein). The goal is to see if adjusting the dose of Furosemide based on your urine sodium levels can lead to better results for people hospitalized with acute decompensated heart failure (when your heart can't pump enough blood to meet your body's needs). Researchers want to know if targeting higher urine sodium levels helps remove more fluid, reduces how long you stay in the hospital, and lowers the chance of coming back to the hospital. You might be able to join if you are an adult (18 or older) admitted to Lakeland Regional Medical Center with acute decompensated heart failure and have signs of too much fluid in your body, like swelling in your legs. The study will measure how much sodium is removed in your urine after 24 hours to see if the new strategies are successful. The current status of the study is unclear.

Study design

This is an interventional study planning to enroll 600 participants. Participants will be randomly assigned to one of three groups: two groups where Furosemide is adjusted based on urine sodium levels, or a standard of care group.

What's involved

If you are in a group where Furosemide is adjusted, your urine sodium will be checked 2-4 hours after receiving the medicine. This process will be repeated for the first 72 hours of your hospital stay.

Compensation

Not stated in the trial record.

Follow-up

The primary endpoint, natriuresis (sodium removal in urine), is measured at 24 hours. Other follow-up details are not specified.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.