Measuring Outcomes With Validated Exercise

This study is looking at how well wrist-worn devices, like the ActiGraph CentrePoint Insight Watch (CPIW), ActiGraph Long-range Energy Alternatives Planning system (LEAP), and GENEActiv, can measure your physical activity. Researchers want to see if these devices accurately track how much you move and how hard you're exercising, compared to a more precise method called indirect calorimetry (which measures oxygen use). This will help them understand how useful these devices are for health. You can join if you are between 18 and 89 years old, can walk on your own, speak English, and have good thinking skills (MoCA score of 26 or higher). The study aims to enroll 54 people, but its current status is unclear.

Study design: This is an observational study, meaning researchers will watch and record information without giving you a specific treatment. It plans to include 54 participants.
What's involved: You will have three in-person visits and spend one week at home wearing devices. During clinic visits, you'll wear three wrist-worn devices, a portable oxygen use monitor, and a heart rate monitor while doing various activities like walking, running, and daily tasks.
Compensation: Not stated in the trial record.
Follow-up: The primary measurement of physical activity is taken at 5 days. It is not specified if there is follow-up beyond this point.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

Measuring Outcomes With Validated Exercise

Recruiting

Not specifiedAges 18–89Observational

Boston University

~54 participants

Updated 2025-12-12 on ClinicalTrials.gov

At a glance

Recruiting sites

1 of 1 listed site is recruiting right now

RecruitingSuspended, closed, or not yet open

What they're measuring

Physical activity (PA) based on algorithms compared to indirect calorimetry

Measured over 5 days

Conditions

Physical Activity

NCT07270185

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

Boston Medical Center and BU Medical Campus
Boston, Massachusettsstudy coordinator listed
Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Study leadership

Kevin C Thomas, PhD MBA · PRINCIPAL_INVESTIGATOR · CABUSM, Anatomy and Neurobiology

Who to contact

Kevin C Thomas, PhD MBA

[email protected]

617-414-2335

Email the study team

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Eligibility criteria

Inclusion

Participant is willing and able to comply with study instructions, study visits, and procedures including wearing a tight-fitting respiratory mask

Able to ambulate independently, including walking/running on a treadmill without assistance.

Demonstrates fluency in English

Montreal Cognitive Assessment (MoCA) score of ≥26

Score of 100 on the Barthel Index

Participant has reliable access to internet

Exclusion

Participation in other digital device trials within 1 week or investigational drug trials within 5 half-lives of last dose.

Allergy to polyurethane resin (strap/wristband component), silicone rubber, nickel and/or steel.

Has any planned surgical, dental, or medical procedure that would overlap with study participation.

Participants with cardiac pacemakers, electronic pumps or any other implanted medical devices.

Has any clinically significant medical disorder, condition, disease or clinically significant finding at intake that precludes participant's participation in study activities including any self-reported diagnosis of cardiovascular disease, metabolic disorder, chronic obstructive pulmonary disease, cerebral vascular accident/stroke, stage 2 hypertension, use of any medication which alters heart rate (HR) response (e.g., Beta blockers and calcium blockers), any history of myocardial infarction high-risk unstable angina, uncontrolled cardiac arrhythmias, active endocarditis, symptomatic severe aortic stenosis, decompensated symptomatic heart failure, acute pulmonary embolus or pulmonary infarction, acute noncardiac disorder that my affect exercise performance/be worsened by exercise (e.g., infection, renal failure), acute myocarditis or pericarditis, left main coronary stenosis or its equivalent, moderate stenotic valvular heart disease, electrolyte abnormalities, tachyarrhythmia or bradyarrhythmia's, atrial fibrillation, high-degree Atrioventricular (AV) block, mobility/orthopedic limitations.

Has any skin conditions, open wounds, or other conditions on the wrists that may interfere with wrist-worn wearable sensors.

Has tuberculosis, oral lesions (sores, bleeding gums), any respiratory illnesses, and/or any other known transmissible infectious diseases during subsequent study visits.

Any changes to recorded health status from intake that would deem participant to be ineligible during subsequent study visits.

Has Asthma

Has claustrophobia

Participants who are investigational site staff members directly involved in the conduct of the study and their family members, site staff members otherwise supervised by the investigator, or participants who are employees directly involved in the conduct of the study.

Has a history of regular alcohol consumption exceeding 7 drinks/week for females or 14 drinks/week for males (1 drink = 5 ounces (150 mL) wine, 12 ounces (360 mL) of beer, or 1.5 ounces (45 mL) of hard liquor) within 12 months of Visit 1 as disclosed by participant during evaluation.

Is a female who is breastfeeding or pregnant, as disclosed by the participant.

Class III Obesity: Body Mass Index (BMI) ≥ 40 kg/m2

Underweight: BMI \< 18.5 kg/m2

Resting systolic blood pressure ≥ 160 mmHg and/or diastolic blood pressure ≥ 100 mmHg

Resting heart rate \<40 or ≥ 110 beats/min (for participants ≥60 years)

Current tobacco/nicotine use

What this trial measures

Physical activity (PA) based on algorithms compared to indirect calorimetry5 days
The performance of current physical activity algorithms (e.g. Staudenmayer, SKDH, Montoye) will be compared to indirect calorimetry applied on multiple test devices to estimate physical activity levels.

Trialytics