Evaluating TRYPTYR for Dry Eye in Sjögren's Syndrome
This study is looking into how well a new eye drop, TRYPTYR (Acoltremon ophthalmic solution 0.003%), works for people who have dry eye caused by Sjögren's Syndrome. We want to see if TRYPTYR can improve the dryness in your eyes. You might be able to join if you are an adult over 18, have been diagnosed with dry eye due to Sjögren's Syndrome in the last two years, and have used or wanted to use artificial tears recently. The main way we'll know if TRYPTYR is successful is by measuring how much your tears improve using a test called a Schirmer's test, both before and after you use the eye drop. The current status of the study is unclear, but it plans to enroll about 35 participants.
- Study design
- This is an interventional study planning to enroll 35 participants. It will evaluate the effect of TRYPTYR eye drops.
- What's involved
- You would have TRYPTYR eye drops instilled before and after a measurement. The primary measurement is taken 3 minutes after instillation at Visit 1.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary endpoint is measured at 3 minutes post-instillation at Visit 1, so follow-up beyond this is not specified.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Evaluating a New Therapy for Dry Eye in Patients With Sjögren's Syndrome
At a glance
Conditions
Where it's being run
1 sites across 1 statesWho to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- Change from pre-instillation to 3 minutes post-TRYPTYR instillation in study eye unanesthetized Schirmer's test at Visit 1 (baseline)3 minutes
Unanesthetized Schirmer's test will be measured prior to instillation and then again 3 minutes after instillation of the TRYPTYR. The difference between the 2 measurements will be compared.