Cannabidiol (CBD) for Alcohol Use Disorder
This study aims to understand how different forms of Cannabidiol (CBD) affect drinking habits in people who regularly consume alcohol. Researchers are testing two types of CBD: Full-Spectrum Cannabidiol (which contains less than 0.3% THC) and Broad-Spectrum Cannabidiol (which contains 0% THC), against a placebo (an inactive substance). They want to see if CBD can help reduce alcohol consumption and related problems. You might be able to join if you are between 21 and 65 years old, have used CBD and cannabis in the past year, and regularly drink alcohol. The study will measure changes in your drinking behavior and alcohol levels over 12 weeks. The current status of this study is unclear, and it plans to enroll 150 participants.
- Study design
- This is an interventional study, meaning participants will receive a specific treatment. It plans to enroll 150 participants, but the phase and whether it's blinded (participants don't know which treatment they receive) are not specified.
- What's involved
- Your participation will involve up to five in-person visits over about 13 weeks, including a screening, medication pickup, midpoint, experimental lab session where you'll be offered alcohol, and a final follow-up. You will take a study medication daily for 8 weeks, complete daily surveys, and have weekly virtual check-ins.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for changes in drinking behavior and alcohol levels for up to 12 weeks.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Cannabidiol and Alcohol Use Disorder Phenotypes
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Hollis C Karoly, PhD · PRINCIPAL_INVESTIGATOR · University of Colorado School of Medicine- Anschutz Medical Campus
Who to contact
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What this trial measures
- Alcohol Self-Administration During the Bar Lab TaskWeek 8
Number of drinks (between 0-8) subjects choose to self-administer during the Bar Lab Alcohol Self-Administration Task at the week 8 study visit.
- Change in Self-Report of Drinking Behavior (Drinks Per Drinking Day)Baseline, Week 4, Week 8, and Week 12
Drinks Per Drinking Day (DPDD) during the 12-week study period as reported on Timeline Follow Back at Baseline (prior to treatment), Week 4, Week 8, and Week 12.
- Change in Phosphatidylethanol (PEth)Baseline, Week 4, Week 8, and Week 12
Phosphatidylethanol (PEth) concentration in blood samples collected at Baseline (prior to treatment), Week 4, Week 8, and Week 12.