Aphasia Physical EXercise Study
This study is looking at how a special high-intensity exercise program, called Aphasia Physical EXercise (APEX), affects recovery in people who have aphasia (difficulty with language) after a stroke. The APEX program is designed to improve physical fitness, thinking skills, and language. We're comparing it to a low-intensity exercise program, which is similar to standard care. The main goal is to see if the high-intensity exercise leads to better physical health, language, thinking, and motor recovery. You might be able to join if you are between 18 and 80 years old, had a stroke at least 6 months ago, have aphasia, and can walk independently. The study is currently recruiting 120 participants, but its exact status is unclear.
- Study design
- This is an interventional study comparing a high-intensity exercise program (APEX) to a low-intensity exercise program. It plans to enroll 120 participants.
- What's involved
- You would participate in an exercise program. Your language abilities will be measured at the start, before treatment, after treatment, and 3 months later.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for 3 months after the exercise program ends.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Aphasia Physical EXercise Study: Randomized Trial
At a glance
Conditions
NCT07281313
Where you'd take part
This study runs at 4 sites. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
California State University, East Bay
Hayward, Californiastudy coordinator listed
Recruiting
University of California, Berkeley
Berkeley, Californiastudy coordinator listed
Recruiting
University of California, San Francisco
San Francisco, Californiastudy coordinator listed
Recruiting
University of San Francisco
San Francisco, Californiastudy coordinator listed
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- Maria Ivanova, PhD · PRINCIPAL_INVESTIGATOR · University of California, Berkeley
Who to contact
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Inclusion
Exclusion
What this trial measures
- Change on the Western Aphasia Battery (WAB) - Aphasia Quotient(T1) Baseline: at the start of the study; (T2) Pre-treatment: 1 week prior to the start of the intervention; (T3) Post-treatment: the week immediately following the intervention; (T4) Follow-up: 3 months after the conclusion of the intervention.
The Aphasia Quotient from the Western Aphasia Battery (a standardized language test) measures overall severity of language impairment in aphasia and ranges from 0 to 100, with lower scores indicative of more severe aphasia.