Persona SoluTion PPS Femur for Knee Replacement

This study is observing adults who are already planning to have a total knee replacement using the Persona® SoluTion® PPS femoral implant. The goal is to see how safe and effective this implant is in the US market. Researchers will look at how your knee function and pain improve after surgery, specifically by measuring changes in your KOOS JR score (a questionnaire about knee symptoms and function) between before surgery and two years later. This is an observational study, meaning you'll receive the standard treatment your doctor recommends. We don't have information on the current recruitment status, but the study plans to include 200 participants.

Study design
This is an observational study involving 200 participants. It is not a randomized trial, meaning participants will receive the Persona® SoluTion® PPS femoral implant as part of their planned total knee arthroplasty.
What's involved
You would need to complete scheduled follow-up evaluations as defined in the study protocol. The primary measurement is taken at two years post-operation.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for at least two years after their surgery to assess changes in their knee function.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07286513

Persona SoluTion PPS Femur PMCF

Enrolling by Invitation
Not specifiedAges 18+Observational
Zimmer Biomet
~200 participants
Updated 2026-08-17 on ClinicalTrials.gov
What's tested:Total knee arthroplasty

At a glance

Recruiting sites
0 of 3 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in KOOS JR Score between pre-op and 2 years post-op
Measured over 2 years
Rhematoid Arthritis
Osteo Arthritis of the Knee
Traumatic Arthritis of Knee (Diagnosis)
Polyarthritis
Collagen Disorders
Avascular Necrosis of Femoral Condyle
Valgus Deformity
Varus Deformity
Flexion Deformity of Knee

NCT07286513

Where you'd take part

This study runs at 3 sites. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Denver Hip and Knee, Inc.

    Denver, Coloradono site contact published

  • Medstar Health Research Institute

    Baltimore, Marylandno site contact published

  • Norton Orthopedic Institute

    Louisville, Kentuckyno site contact published

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

This trial hasn't published a contact. View it on ClinicalTrials.gov

  • Change in KOOS JR Score between pre-op and 2 years post-op2 years

    A 7-item shortened version of the Knee injury and Osteoarthritis Outcome Score (KOOS), specifically designed to assess knee health in patients undergoing total knee arthroplasty (TKA). Raw scores are converted to an interval score ranging from 0 to 100, where 0 represents complete knee disability and 100 represents perfect knee health (higher scores indicate less pain and better function).