A Study of Bimekizumab for Psoriatic Arthritis and Axial Spondyloarthritis

This study is looking at bimekizumab, a drug that works by targeting a specific pathway in the body called MEK. Researchers want to see if giving bimekizumab in different ways (intravenously, meaning into a vein, or subcutaneously, meaning under the skin) is safe and moves through the body similarly over time. This study is for adults aged 18 and older who have active psoriatic arthritis (a type of arthritis affecting some people with psoriasis) or axial spondyloarthritis (a type of arthritis that mainly affects the spine). You can join if you haven't taken certain biologic medications before, or if you stopped them a while ago. The main goal is to measure how much bimekizumab is in your body at Week 16. The study plans to enroll 392 participants, but its current status is unclear.

Study design
This is an interventional study, meaning participants will receive a specific treatment. It plans to enroll 392 participants.
What's involved
Participants will receive bimekizumab at pre-specified time points. The primary endpoint is measured at Week 16.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint is measured at Week 16, but longer follow-up is not specified.

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NCT07290036

A Study to Learn if Bimekizumab Given in Different Ways is Safe and Moves Similarly Throughout the Body Over Time in Adults

Recruiting
PHASE1Ages 18+InterventionalTreatment
UCB Biopharma SRL
~392 participants
Updated 2026-07-06 on ClinicalTrials.gov
What's tested:Bimekizumab regimen 1 ivBimekizumab regimen 2 ivBimekizumab regimen 3 sc

At a glance

Recruiting sites
63 of 63 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Steady-state Trough Concentration (Ctrough,ss) at Week 16
Measured over Week 16
Psoriatic Arthritis
Axial Spondyloarthritis
63 sites across 20 states
Poland18
California9
Bulgaria5
Texas4
Czechia4
Germany4
Florida3
Tennessee2
  • UCB Cares · STUDY_DIRECTOR · 001 844 599 22733 (UCB)

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  • Steady-state Trough Concentration (Ctrough,ss) at Week 16Week 16

    Steady-state trough concentration (Ctrough,ss) will be reported.