Doppler Evaluation for Congestive Acute Kidney Injury in Critical Illness
This study is looking at how using a special ultrasound score, called VExUS (Venous Excess Ultrasound), can help doctors manage fluids in critically ill patients in the ICU who have acute kidney injury (AKI). You would be in one of two groups: one where your care team gets recommendations based on your VExUS score for fluid management, or another where they don't. The study aims to see if using VExUS to guide fluid balance (how much fluid you receive or lose) can improve important outcomes like survival, the need for kidney dialysis (renal replacement therapy), and long-term kidney function. We are looking for 100 adult patients who are in the ICU with AKI.
- Study design
- This is an interventional study with 100 participants, combining observational and randomized components. It compares two groups: one where doctors receive VExUS recommendations and one where they do not.
- What's involved
- You would undergo two VExUS ultrasound assessments: one at enrollment and another 48-72 hours later. Blood tests and fluid balance records would also be collected.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your in-hospital mortality, need for renal replacement therapy, and persistent renal dysfunction will be measured for up to 30 days.
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Doppler Evaluation for Congestive Acute Kidney Injury in Critical Illness
At a glance
Conditions
Where it's being run
1 sites across 1 statesWho to contact
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What this trial measures
- In-hospital Mortalityup to 30 days
In-hospital mortality: Death from any cause before hospital discharge, within the 30-day window.
- Renal Replacement Therapyup to 30 days
New receipt of Renal Replacement Therapy (RRT): Receiving dialysis or another form of RRT for the first time.
- Persistent Renal Dysfunctionup to 30 days
Persistent renal dysfunction: The final serum creatinine value before hospital discharge (within 30 days) is 200% (twice) or more of the patient's baseline creatinine value.