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Comparing Post-Filter Hematocrit Measurements in CRRT

This study is for adults (18 and older) who are receiving continuous renal replacement therapy (CRRT) for kidney failure. Researchers are comparing two ways to measure "post-filter hematocrit" (Hct), which is the thickness of your blood after it goes through the CRRT filter. One way is by calculating it using a formula (Calculated Post-Filter Hematocrit), and the other is by taking a direct blood sample from the CRRT machine (Measured Post-Filter Hematocrit). The goal is to see how well these two methods agree. This is important because post-filter Hct might help doctors prevent filter clotting, a common problem with CRRT. The study aims to enroll 20 participants and is currently unclear on its recruitment status.

Study design
This is an interventional study comparing two measurement methods. It plans to include 20 participants.
What's involved
You would participate in a single study procedure where four post-filter blood samples are collected over about 40 minutes. Your participation ends after the final blood draw, generally within one day.
Compensation
Not stated in the trial record.
Follow-up
Participation ends after the final blood draw, generally no longer than 1 day.

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NCT07293936

Post-Filter Hematocrit

Recruiting
NAAges 18+Interventional
Gwyndolyn M. Radford
~20 participants
Updated 2025-12-19 on ClinicalTrials.gov
What's tested:Calculated Post-Filter HematocritMeasured Post-Filter Hematocrit

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Agreement between measured and calculated post-filter hematocrit values.
Measured over Participation begins at consent and includes a single study procedure in which four post-filter blood samples are collected over ~40 minutes. Participation ends after the final draw. Generally, no longer than 1 day.

Conditions

Continuous Renal Replacement Therapy
Renal Failure
Hemofilter Clotting

Explore related trials

Hemofilter ClottingRenal Failure

Where it's being run

1 sites across 1 states
Iowa1

Who to contact

Gwyndolyn M Radford, MD
[email protected]
7858179620
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Eligibility criteria

Inclusion

patients initiated on CRRT age equal than or greater to 18 years of age

Exclusion

patients on ECMO

What this trial measures

  • Agreement between measured and calculated post-filter hematocrit values.Participation begins at consent and includes a single study procedure in which four post-filter blood samples are collected over ~40 minutes. Participation ends after the final draw. Generally, no longer than 1 day.

    Use Bland-Altman analysis to assess agreement and quantify bias and limits of agreement. Calculate correlation coefficients (Pearson or Spearman) to evaluate the strength of association.