Automated Applanation Tonometry for Glaucoma
This study is comparing new ways to measure eye pressure (intraocular pressure or IOP) to the standard methods. Eye pressure is important for conditions like glaucoma and glaucoma suspect. Researchers are testing two new devices: a "Fixed force GAT" and an "Upright applanating prototype." These will be compared to the standard Goldmann Applanation Tonometry (GAT) and a Pneumotonometer, which are common ways to check eye pressure. The goal is to find more accurate, consistent, and portable ways to measure IOP. You may be able to join if you are 18 or older, coming in for a routine eye exam, and do not have certain eye conditions like corneal scarring or active eye infections. The study aims to enroll 200 participants, but its current status is unclear.
- Study design
- This is an interventional study planning to enroll 200 participants. It is a prospective study, meaning participants are recruited as they come in for eye appointments.
- What's involved
- You will have your eye pressure measured using four different methods: Standard GAT, Fixed force GAT, Upright applanating prototype, and Pneumotonometer. Some methods involve a numbing agent and a probe touching your eye.
- Compensation
- Not stated in the trial record.
- Follow-up
- Eye pressure measurements are taken at baseline (at the start of your participation).
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Automated Applanation Tonometry - Updated
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Joanne Wen, MD · PRINCIPAL_INVESTIGATOR · Duke Eye Center
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Intraocular pressure (IOP) as measured by standard GATBaseline
this is the standard method for IOP measurement in clinical practice. The eye is given topical fluorescein/anesthetic, the GAT prism contacts the eye while the observer looks through the slit lamp machine ocular using blue light illumination to visual the applanation mires. The GAT dial is adjusted until mire alignment is achieved and the IOP measurement is read off the GAT dial.
- Intraocular pressure (IOP) as measured by fixed force GATBaseline
From the patient perspective, this method will feel identical to the standard GAT. The eye is given topical fluorescein/anesthetic. The GAT dial is set at 1.8 or 2.0, a C-MOS camera is connected to one of the oculars of the slit lamp machine and under blue light illumination, the GAT prism contacts the eye while the CMOS camera makes a video of the mire appearance through the ocular.
- Intraocular pressure as measured by upright applanatingBaseline
With this prototype, an applanating prism (custom manufactured with medical grade acrylic in an ISO-13485 certified facility) is attached to a fixed-force spring that creates a force equivalent to 1.8 or 2.0 on the GAT dial. Blue LED lights on the prototype are used to create the blue illumination similar to the blue light used in clinical practice on the slit lamp or Perkins tonometer. A C-MOS camera is aligned with the GAT prism to image the applanation mires. The eye is given topical fluorescein/anesthetic. Like fixed-force GAT, the GAT prism contacts the eye while the CMOS camera makes a video of the mire appearance. The diameters of the recorded mire images are measured and the IOP is calculated based on the mire diameter.
- Intraocular pressure as measured by supine PneumotonometerBaseline