Study of VYD2311 for Preventing COVID-19

This study is testing an investigational drug called VYD2311 to see if it can help prevent COVID-19. VYD2311 is a monoclonal antibody, which means it's a type of protein designed to attach to the COVID-19 virus and stop it from infecting your cells. We are looking for adults and adolescents aged 12 to 100 years old to participate. You would receive either VYD2311 or a placebo (an inactive substance like saline) through shots into your muscle on Day 1, Day 30, and Day 60. The main goal is to see how well VYD2311 prevents symptomatic COVID-19 for 90 days after the first shot.

Study design
This interventional study plans to enroll 1770 participants. It compares different dosing schedules of VYD2311 against a placebo.
What's involved
Participants will receive three intramuscular injections on Day 1, Day 30, and Day 60. The study will monitor for symptomatic COVID-19 for 90 days.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for RT-PCR-confirmed symptomatic COVID-19 through Day 90.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07298434

Study of VYD2311 for the Prevention of COVID-19

Active, Not Recruiting
PHASE3Ages 12+InterventionalPrevention
Invivyd, Inc.
~1,770 participants
Updated 2026-06-10 on ClinicalTrials.gov
What's tested:VYD2311-SDVYD2311-MDPlacebo

At a glance

Recruiting sites
0 of 20 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
RT-PCR-confirmed symptomatic COVID-19 through Day 90
Measured over 90 days
COVID-19
20 sites across 16 states
Texas4
California2
Florida1
Georgia1
Illinois1
Kansas1
Maryland1
Massachusetts1

This trial hasn't published a contact. View it on ClinicalTrials.gov

  • RT-PCR-confirmed symptomatic COVID-19 through Day 9090 days